STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45512.1TIGRFAM:TIGR01181:dTDP-glucose 4,6-dehydratase; COG:COG1088: dTDP-D-glucose 46-dehydratase [Cell envelope biogenesis outer membrane]; Pfam:PF01370:NAD-dependent epimerase/dehydratase; SUPERFAMILY:SSF51735:No Description;KEGG: 00521; KEGG: 00523; MetaCyc: PWY-3221; UniPathway: UPA00124; dTDP_gluc_dehyt; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (359 aa)    
Predicted Functional Partners:
AHY45513.1
rmlA: glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 0.999
AHY45514.1
rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
AHY45518.1
rmlD: dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
 
 0.990
AHY47994.1
COG:COG1898: dTDP-4-dehydrorhamnose 35-epimerase and related enzymes [Cell envelope biogenesis outer membrane]; Pfam:PF00908:dTDP-4-dehydrorhamnose 3,5-epimerase-related; Pfam:PF00908:dTDP-4-dehydrorhamnose 3,5-epimerase-related; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
 
 
 0.974
AHY45744.1
COG:COG0451: Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis outer membrane / Carbohydrate transport and metabolism]; Pfam:PF01370:NAD-dependent epimerase/dehydratase; Pfam:PF01370:NAD-dependent epimerase/dehydratase; SUPERFAMILY:SSF51735:No Description.
 
 
0.928
AHY45743.1
TIGRFAM:TIGR03026:Nucleotide sugar dehydrogenase; COG:COG1004: Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis outer membrane]; Pfam:PF03721:UDP-glucose/GDP-mannose dehydrogenase, N-terminal; PIRSF:PIRSF000124:Nucleotide sugar dehydrogenase; SMART:SM00984:UDP-glucose/GDP-mannose dehydrogenase, C-terminal; SUPERFAMILY:SSF51735:No Description.
  
  
 0.833
AHY46622.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
  
 0.792
AHY45447.1
Sulfotransferase family; COG:COG3551: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13469:Sulfotransferase family; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
  
 0.750
AHY46726.1
Nucleotidyl transferase; COG:COG1208: Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis outer membrane / Translation ribosomal structure and biogenesis]; Pfam:PF00483:Nucleotidyl transferase; SUPERFAMILY:SSF53448:No Description;Reactome: REACT_17015.
  
  
 0.704
AHY47733.1
Mannose-1-phosphate guanylyltransferase; COG:COG1208: Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis outer membrane / Translation ribosomal structure and biogenesis]; Pfam:PF00483:Nucleotidyl transferase; Pfam:PF00483:Nucleotidyl transferase; SUPERFAMILY:SSF53448:No Description.
  
  
 0.704
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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