STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AHY45561.1DHPS: dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (310 aa)    
Predicted Functional Partners:
AHY46827.1
folC: bifunctional protein FolC; TIGRFAM:TIGR01499:Folylpolyglutamate synthetase; COG:COG0285: Folylpolyglutamate synthase [Coenzyme metabolism]; Pfam:PF02875:Mur ligase, C-terminal; SUPERFAMILY:SSF53623:Mur ligase, central;KEGG: 00790; MetaCyc: PWY-2161; UniPathway: UPA00850.
 
 0.997
AHY47253.1
folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; TIGRFAM:TIGR01498:7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; COG:COG0801: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism]; Pfam:PF01288:7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; SUPERFAMILY:SSF55083:7, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK;KEGG: 00790; MetaCyc: PWY-6147; UniPathway: UPA00077.
 
 0.996
AHY47406.1
folB: dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.989
AHY47254.1
DHPS: dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 
0.914
folE
COG:COG0302: GTP cyclohydrolase I [Coenzyme metabolism]; Pfam:PF01227:GTP cyclohydrolase I/Nitrile oxidoreductase; Hamap:MF_00223:GTP cyclohydrolase I; Pfam:PF01227:GTP cyclohydrolase I/Nitrile oxidoreductase; ProSitePatterns:PS00859:GTP cyclohydrolase I, conserved site; SUPERFAMILY:SSF55620:No Description.
  
 0.891
AHY45562.1
Permease; COG:COG2252: Permeases [General function prediction only]; Pfam:PF00860:Xanthine/uracil/vitamin C permease; Pfam:PF00860:Xanthine/uracil/vitamin C permease; PIRSF:PIRSF005353:Purine permease PbuG-like.
       0.778
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.514
AHY47163.1
Glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase; TIGRFAM:TIGR00566:Anthranilate synthase/para-aminobenzoate synthase like domain; COG:COG0512: Anthranilate/para-aminobenzoate synthases component II [Amino acid transport and metabolism / Coenzyme metabolism]; Pfam:PF00117:Glutamine amidotransferase; PRINTS:PR00097:Anthranilate synthase component II signature; ProSiteProfiles:PS51273:Glutamine amidotransferase; SUPERFAMILY:SSF52317:No Description;KEGG: 00400; MetaCyc: PWY-5958; UniPathway: UPA00035; trpG_papA.
 
  
 0.514
AHY45563.1
Bacteriocin-protection, YdeI or OmpD-Associated; COG:COG4430: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13376:Bacteriocin-protection, YdeI or OmpD-Associated; SUPERFAMILY:SSF141694:No Description.
       0.489
AHY45979.1
TIGRFAM:TIGR01304:IMP dehydrogenase-related 2; COG:COG0516: IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]; Pfam:PF00478:IMP dehydrogenase/GMP reductase; SUPERFAMILY:SSF51412:No Description;KEGG: 00121; KEGG: 00231; KEGG: 00520; KEGG: 00592; KEGG: 00633; KEGG: 00860; KEGG: 00906; KEGG: 00950; KEGG: 00981; IMP_DH_rel_2.
  
  
 0.487
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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