STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45565.1COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase. (339 aa)    
Predicted Functional Partners:
AHY45564.1
ABC-2 family transporter protein; COG:COG1277: ABC-type transport system involved in multi-copper enzyme maturation permease component [General function prediction only]; Pfam:PF12679:ABC-2 family transporter protein.
  
 
 0.911
AHY46053.1
TIGRFAM:TIGR01727:Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; COG:COG0444: ABC-type dipeptide/oligopeptide/nickel transport system ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Pfam:PF08352:Oligopeptide/dipeptide ABC transporter, C-terminal; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; oligo_HPY; Belongs to the ABC transporter superfamily.
    
0.906
AHY47975.1
ATPase family associated with various cellular activities (AAA); COG:COG1222: ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification protein turnover chaperones]; Pfam:PF00004:ATPase, AAA-type, core; ProSitePatterns:PS00674:ATPase, AAA-type, conserved site; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.724
AHY47806.1
TIGRFAM:TIGR01726:Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; COG:COG0765: ABC-type amino acid transport system permease component [Amino acid transport and metabolism]; Pfam:PF00528:Binding-protein-dependent transport systems inner membrane component; ProSiteProfiles:PS50928:Binding-protein-dependent transport systems inner membrane component; SUPERFAMILY:SSF161098:No Description; HEQRo_perm_3TM.
      0.560
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.545
AHY48017.1
COG:COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification protein turnover chaperones]; Pfam:PF00226:DnaJ domain; PRINTS:PR00625:DnaJ domain; ProSiteProfiles:PS50076:DnaJ domain; SMART:SM00271:DnaJ domain; SUPERFAMILY:SSF46565:DnaJ domain.
  
   0.541
AHY45566.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.534
cysS
cysS: cysteine--tRNA ligase; TIGRFAM:TIGR00435:Cysteine-tRNA ligase; COG:COG0215: Cysteinyl-tRNA synthetase [Translation ribosomal structure and biogenesis]; Pfam:PF01406:Cysteinyl-tRNA synthetase/mycothiol ligase; Hamap:MF_00041:Cysteine-tRNA ligase; PRINTS:PR00983:Cysteinyl-tRNA synthetase/mycothiol ligase; SMART:SM00840:Cysteinyl-tRNA synthetase, class Ia, DALR; SUPERFAMILY:SSF52374:No Description;KEGG: 00970; Reactome: REACT_71; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
   
 0.517
rplN
Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
 
   0.499
AHY47492.1
COG:COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification protein turnover chaperones]; Pfam:PF00226:DnaJ domain; PRINTS:PR00625:DnaJ domain; ProSiteProfiles:PS50076:DnaJ domain; SMART:SM00271:DnaJ domain; SUPERFAMILY:SSF46565:DnaJ domain.
  
   0.499
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (28%) [HD]
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