STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45602.1Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (508 aa)    
Predicted Functional Partners:
AHY45603.1
COG:COG0506: Proline dehydrogenase [Amino acid transport and metabolism]; Pfam:PF01619:Proline dehydrogenase; Pfam:PF01619:Proline dehydrogenase; PIRSF:PIRSF000196:Proline dehydrogenase, predicted; SUPERFAMILY:SSF51730:No Description.
  
  
 0.936
AHY45604.1
TIGRFAM:TIGR01237:Delta-1-pyrroline-5-carboxylate dehydrogenase 2; COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase;KEGG: 00250; KEGG: 00330; UniPathway: UPA00261; Belongs to the aldehyde dehydrogenase family.
  
  
 0.815
AHY47667.1
COG:COG1966: Carbon starvation protein predicted membrane protein [Signal transduction mechanisms]; Pfam:PF02554:Carbon starvation protein CstA; Pfam:PF02554:Carbon starvation protein CstA.
 
    0.698
apt
Apt: adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.661
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.616
AHY45599.1
COG:COG0733: Na+-dependent transporters of the SNF family [General function prediction only]; Pfam:PF00209:Sodium:neurotransmitter symporter; Pfam:PF00209:Sodium:neurotransmitter symporter; PRINTS:PR00176:Sodium:neurotransmitter symporter; ProSiteProfiles:PS50267:Sodium:neurotransmitter symporter; SUPERFAMILY:SSF161070:No Description.
 
  
 0.585
AHY47803.1
COG:COG1126: ABC-type polar amino acid transport system ATPase component [Amino acid transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
  
 0.552
AHY45598.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.540
AHY45891.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50112:PAS domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
  
  
 0.522
AHY46900.1
TIGRFAM:TIGR01798:Citrate synthase, type II; COG:COG0372: Citrate synthase [Energy production and conversion]; Pfam:PF00285:Citrate synthase-like; PIRSF:PIRSF001369:Citrate synthase, bacterial-type; PRINTS:PR00143:Citrate synthase-like; ProSitePatterns:PS00480:Citrate synthase active site; SUPERFAMILY:SSF48256:Citrate synthase-like, core;KEGG: 00020; KEGG: 00630; MetaCyc: PWY-5750; UniPathway: UPA00223; cit_synth_I; Belongs to the citrate synthase family.
   
  
 0.508
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.