STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45624.1MerR HTH family regulatory protein; COG:COG0789: Predicted transcriptional regulators [Transcription]; Pfam:PF13411:MerR HTH family regulatory protein; ProSitePatterns:PS00552:Transcription regulator HTH, MerR; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00422:Transcription regulator HTH, MerR; SUPERFAMILY:SSF51182:RmlC-like cupin domain. (274 aa)    
Predicted Functional Partners:
AHY47735.1
Helix-turn-helix domain; COG:COG0662: Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Pfam:PF13560:Helix-turn-helix domain; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00530:Helix-turn-helix; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
 
  
 0.859
AHY46526.1
Helix-turn-helix protein; COG:COG1396: Predicted transcriptional regulators [Transcription]; Pfam:PF01381:Helix-turn-helix; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00530:Helix-turn-helix; SUPERFAMILY:SSF47413:Lambda repressor-like, DNA-binding domain.
 
  
 0.838
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.798
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.794
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
   
 
 0.738
AHY46246.1
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.715
AHY46501.1
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.713
AHY45656.1
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.711
sigA
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
 
 0.711
AHY45611.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2208: Serine phosphatase RsbU regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Pfam:PF07228:Protein phosphatase 2C (PP2C)-like; ProSiteProfiles:PS50112:PAS domain; SMART:SM00331:Protein phosphatase 2C (PP2C)-like; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.702
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.