STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45633.1GABAtrnsam: 4-aminobutyrate transaminase; TIGRFAM:TIGR00700:4-aminobutyrate aminotransferase, bacterial; COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase;KEGG: 00250; KEGG: 00280; KEGG: 00410; KEGG: 00640; KEGG: 00650; MetaCyc: PWY-4321; UniPathway: UPA00733; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)    
Predicted Functional Partners:
AHY45918.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase.
 
 0.926
AHY46946.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00070:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase.
 
 0.926
AHY47657.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.926
AHY48015.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase.
 
 0.926
AHY47355.1
COG:COG0388: Predicted amidohydrolase [General function prediction only]; Pfam:PF00795:Carbon-nitrogen hydrolase; Pfam:PF00795:Carbon-nitrogen hydrolase; ProSiteProfiles:PS50263:Carbon-nitrogen hydrolase; SUPERFAMILY:SSF56317:Carbon-nitrogen hydrolase.
  
 
 0.925
AHY45351.1
COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.922
panC
panC: pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.902
AHY47662.1
COG:COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Pfam:PF03446:6-phosphogluconate dehydrogenase, NADP-binding; Pfam:PF03446:6-phosphogluconate dehydrogenase, NADP-binding; PIRSF:PIRSF000103:Hydroxy monocarboxylic acid anion dehydrogenase, HIBADH-type; SUPERFAMILY:SSF51735:No Description.
     
  0.900
AHY47357.1
COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.852
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.812
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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