STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45637.1COG:COG4668: Mannitol/fructose-specific phosphotransferase system IIA domain [Carbohydrate transport and metabolism]; Pfam:PF00359:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Pfam:PF00359:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; ProSitePatterns:PS00372:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; ProSiteProfiles:PS51094:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SUPERFAMILY:SSF55804:Phosphotransferase/anion transporter. (144 aa)    
Predicted Functional Partners:
AHY45635.1
TIGRFAM:TIGR00851:Phosphotransferase system, mannitol-specific enzyme IIC; COG:COG2213: Phosphotransferase system mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Pfam:PF02302:Phosphotransferase system, EIIB component, type 2/3; ProSiteProfiles:PS51099:Phosphotransferase system, EIIB component, type 2; SUPERFAMILY:SSF52794:No Description;KEGG: 00010; KEGG: 00051; KEGG: 00052; KEGG: 00053; KEGG: 00500; KEGG: 00520.
 
 0.999
mtlD
COG:COG0246: Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Pfam:PF08125:Mannitol dehydrogenase, C-terminal; Hamap:MF_00196:Mannitol-1-phosphate 5-dehydrogenase; Pfam:PF08125:Mannitol dehydrogenase, C-terminal; PRINTS:PR00084:Mannitol dehydrogenase; SUPERFAMILY:SSF48179:6-phosphogluconate dehydrogenase, C-terminal-like.
 
 0.999
AHY46936.1
TIGRFAM:TIGR01427:Phosphotransferase system, fructose IIC component; COG:COG1299: Phosphotransferase system fructose-specific IIC component [Carbohydrate transport and metabolism]; Pfam:PF02302:Phosphotransferase system, EIIB component, type 2/3; ProSiteProfiles:PS51099:Phosphotransferase system, EIIB component, type 2; SUPERFAMILY:SSF52794:No Description; PTS_IIC_fructo.
  
 0.999
AHY45636.1
PRD domain; COG:COG3711: Transcriptional antiterminator [Transcription]; Pfam:PF00874:PRD; ProSiteProfiles:PS51372:PRD; SUPERFAMILY:SSF63520:PRD.
 
  
 0.981
AHY46935.1
Phosphocarrier, HPr family; TIGRFAM:TIGR01003:Phosphotransferase system, phosphocarrier HPr protein; COG:COG1925: Phosphotransferase system HPr-related proteins [Carbohydrate transport and metabolism]; Pfam:PF00381:Phosphotransferase system, phosphocarrier HPr protein; PRINTS:PR00107:Phosphotransferase system, phosphocarrier HPr protein; ProSiteProfiles:PS51350:Phosphotransferase system, phosphocarrier HPr protein-like; SUPERFAMILY:SSF55594:Phosphotransferase system, phosphocarrier HPr protein-like; PTS_HPr_family.
   
 0.959
AHY46934.1
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
   
 0.949
AHY46938.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00584:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
 
  
 0.867
AHY45801.1
1-PFK: hexose kinase, 1-phosphofructokinase family; TIGRFAM:TIGR03168:Tagatose/fructose phosphokinase; COG:COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; PIRSF:PIRSF000535:Tagatose/fructose phosphokinase; ProSitePatterns:PS00583:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description;KEGG: 00052; UniPathway: UPA00704.
 
  
 0.851
AHY46937.1
TIGRFAM:TIGR00848:Phosphotransferase system, IIA component fructose subfamily; COG:COG1762: Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Pfam:PF00359:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; ProSiteProfiles:PS51094:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SUPERFAMILY:SSF55804:Phosphotransferase/anion transporter;KEGG: 00030; KEGG: 00540; KEGG: 00760.
 
  
 0.683
AHY45639.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.565
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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