STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45660.1COG:COG0607: Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Pfam:PF00581:Rhodanese-like domain; Pfam:PF00581:Rhodanese-like domain; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF52821:Rhodanese-like domain. (121 aa)    
Predicted Functional Partners:
thiG
thiS: thiamine biosynthesis protein ThiS; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.998
AHY47427.1
ThiF family; COG:COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Pfam:PF00899:UBA/THIF-type NAD/FAD binding fold; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF69572:Molybdenum cofactor biosynthesis, MoeB.
   
0.940
AHY45672.1
COG:COG0314: Molybdopterin converting factor large subunit [Coenzyme metabolism]; Pfam:PF02391:Molybdopterin biosynthesis MoaE; Pfam:PF02391:Molybdopterin biosynthesis MoaE; SUPERFAMILY:SSF54690:Molybdopterin biosynthesis MoaE.
  
 0.834
AHY45673.1
TIGRFAM:TIGR01682:Molybdopterin converting factor, subunit 1; COG:COG1977: Molybdopterin converting factor small subunit [Coenzyme metabolism]; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; SUPERFAMILY:SSF54285:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp;UniPathway: UPA00344.
 
 
 0.765
AHY47426.1
COG:COG1977: Molybdopterin converting factor small subunit [Coenzyme metabolism]; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; Pfam:PF02597:ThiamineS/Molybdopterin converting factor subunit 1; SUPERFAMILY:SSF54285:Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp.
  
 
 0.720
hisI
TIGRFAM:TIGR03188:Phosphoribosyl-ATP pyrophosphohydrolase; COG:COG0139: Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Pfam:PF01502:Phosphoribosyl-AMP cyclohydrolase domain; Hamap:MF_01020:Phosphoribosyl-ATP pyrophosphohydrolase; SUPERFAMILY:SSF141734:No Description;KEGG: 00340; UniPathway: UPA00031; histidine_hisI; In the N-terminal section; belongs to the PRA-CH family.
  
 
 0.714
AHY47716.1
TIGRFAM:TIGR00097:Phosphomethylpyrimidine kinase type-2; COG:COG0351: Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [Coenzyme metabolism]; Pfam:PF08543:Phosphomethylpyrimidine kinase type-1; SUPERFAMILY:SSF53613:No Description;KEGG: 00730; UniPathway: UPA00060; HMP-P_kinase.
  
  
 0.708
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.703
AHY45374.1
COG:COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; PIRSF:PIRSF005572:Cysteine desulfurase, NifS; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
   
 0.692
AHY46640.1
COG:COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; PIRSF:PIRSF005572:Cysteine desulfurase, NifS; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
   
 0.692
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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