STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45667.1TIGR00488: putative HD superfamily hydrolase; TIGRFAM:TIGR00488:Conserved hypothetical protein CHP00488; COG:COG1713: Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism]; Pfam:PF01966:HD domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description. (202 aa)    
Predicted Functional Partners:
nadD
TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.975
AHY45668.1
Competence/damage-inducible protein CinA N-terminal domain; TIGRFAM:TIGR00200:Competence-induced protein CinA; COG:COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Pfam:PF02464:CinA, C-terminal; Hamap:MF_00226_B:Competence-induced protein CinA; PIRSF:PIRSF006728:Competence-induced protein CinA; SMART:SM00852:Molybdopterin binding domain; SUPERFAMILY:SSF142433:No Description; cinA_nterm.
 
     0.692
whiA
Sporulation regulator WhiA; Involved in cell division and chromosome segregation.
  
     0.688
AHY46658.1
TIGRFAM:TIGR03599:DAK2 domain-containing protein YloV; COG:COG1461: Predicted kinase related to dihydroxyacetone kinase [General function prediction only]; Pfam:PF13684:Dihydroxyacetone kinase family; ProSiteProfiles:PS51480:Dak phosphatase; SUPERFAMILY:SSF101473:Dak phosphatase.
 
   
 0.617
rsfS
Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.616
AHY47194.1
COG:COG0619: ABC-type cobalt transport system permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Pfam:PF02361:ABC/ECF transporter, transmembrane component; Pfam:PF02361:ABC/ECF transporter, transmembrane component.
  
     0.554
aroE
aroE: shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
    0.519
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
     0.466
AHY47196.1
COG:COG1122: ABC-type cobalt transport system ATPase component [Inorganic ion transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
     0.426
AHY45398.1
TIGRFAM:TIGR00350:Cell envelope-related transcriptional attenuator; COG:COG1316: Transcriptional regulator [Transcription]; Pfam:PF03816:Cell envelope-related transcriptional attenuator; lytR_cpsA_psr.
 
     0.406
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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