STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AHY45701.1Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (429 aa)    
Predicted Functional Partners:
AHY45700.1
TIGRFAM:TIGR00239:2-oxoglutarate dehydrogenase, E1 component; COG:COG0567: 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component and related enzymes [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; PIRSF:PIRSF000157:2-oxoglutarate dehydrogenase, E1 component; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description;KEGG: 00020; KEGG: 00310; KEGG: 00380; MetaCyc: PWY-5084; 2oxo_dh_E1.
 0.999
AHY45678.1
TIGRFAM:TIGR01350:Dihydrolipoamide dehydrogenase; COG:COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes [Energy production and conversion]; Pfam:PF07992:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; PRINTS:PR00411:Pyridine nucleotide disulphide reductase class-I signature; ProSitePatterns:PS00076:Pyridine nucleotide-disulphide oxidoreductase, class I, active site; SUPERFAMILY:SSF51905:No Description;KEGG: 00010; KEGG: 00020; KEGG: 00260; KEGG: 00280; KEGG: 00620; MetaCyc: PWY-5046; MetaCy [...]
 0.990
sucC
sucCoAbeta: succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.967
AHY47758.1
Dehydrogenase E1 component; COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF00676:Dehydrogenase, E1 component; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 0.960
sucD
sucCoAalpha: succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.956
AHY46942.1
COG:COG1960: Acyl-CoA dehydrogenases [Lipid metabolism]; Pfam:PF00441:Acyl-CoA oxidase/dehydrogenase, type 1; Pfam:PF00441:Acyl-CoA oxidase/dehydrogenase, type 1; ProSitePatterns:PS00072:Acyl-CoA dehydrogenase, conserved site; SUPERFAMILY:SSF56645:Acyl-CoA dehydrogenase/oxidase.
   
  0.909
AHY47126.1
COG:COG1960: Acyl-CoA dehydrogenases [Lipid metabolism]; Pfam:PF00441:Acyl-CoA oxidase/dehydrogenase, type 1; Pfam:PF00441:Acyl-CoA oxidase/dehydrogenase, type 1; ProSitePatterns:PS00073:Acyl-CoA dehydrogenase, conserved site; SUPERFAMILY:SSF56645:Acyl-CoA dehydrogenase/oxidase.
   
  0.909
AHY47372.1
COG:COG1960: Acyl-CoA dehydrogenases [Lipid metabolism]; Pfam:PF02771:Acyl-CoA dehydrogenase, N-terminal; Pfam:PF02771:Acyl-CoA dehydrogenase, N-terminal; ProSitePatterns:PS00072:Acyl-CoA dehydrogenase, conserved site; SUPERFAMILY:SSF56645:Acyl-CoA dehydrogenase/oxidase.
   
  0.909
AHY45707.1
AcCoA-C-Actrans: acetyl-CoA C-acetyltransferase; TIGRFAM:TIGR01930:Thiolase; COG:COG0183: Acetyl-CoA acetyltransferase [Lipid metabolism]; Pfam:PF00108:Thiolase, N-terminal; PIRSF:PIRSF000429:Thiolase; ProSitePatterns:PS00099:Thiolase, active site; SUPERFAMILY:SSF53901:Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.806
AHY45887.1
AcCoA-C-Actrans: acetyl-CoA C-acetyltransferase; TIGRFAM:TIGR01930:Thiolase; COG:COG0183: Acetyl-CoA acetyltransferase [Lipid metabolism]; Pfam:PF00108:Thiolase, N-terminal; PIRSF:PIRSF000429:Thiolase; ProSitePatterns:PS00099:Thiolase, active site; SUPERFAMILY:SSF53901:Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.806
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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