STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45708.1COG:COG2902: NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; PIRSF:PIRSF036761:Bacterial NAD-glutamate dehydrogenase; SUPERFAMILY:SSF51735:No Description. (1625 aa)    
Predicted Functional Partners:
AHY46724.1
FHA domain; COG:COG1716: FOG: FHA domain [Signal transduction mechanisms]; Pfam:PF00498:Forkhead-associated (FHA) domain; ProSiteProfiles:PS50006:Forkhead-associated (FHA) domain; SMART:SM00240:Forkhead-associated (FHA) domain; SUPERFAMILY:SSF49879:SMAD/FHA domain.
    
 
 0.983
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
     
 0.950
AHY48034.1
COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; Pfam:PF00120:Glutamine synthetase, catalytic domain; SUPERFAMILY:SSF55931:No Description.
     
 0.932
AHY46403.1
TIGRFAM:TIGR00653:Glutamine synthetase type I; COG:COG0174: Glutamine synthetase [Amino acid transport and metabolism]; Pfam:PF00120:Glutamine synthetase, catalytic domain; ProSitePatterns:PS00181:Glutamine synthetase, glycine-rich site; SUPERFAMILY:SSF55931:No Description;KEGG: 00250; KEGG: 00330; KEGG: 00910; MetaCyc: PWY-3282.
     
 0.930
AHY47838.1
TIGRFAM:TIGR01317:Glutamate synthase, NADH/NADPH, small subunit 1; COG:COG0493: NADPH-dependent glutamate synthase beta chain and related oxidoreductases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF07992:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; PRINTS:PR00419:Adrenodoxin reductase family signature; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF51971:No Description;UniPathway: UPA00045.
     
 0.912
AHY45604.1
TIGRFAM:TIGR01237:Delta-1-pyrroline-5-carboxylate dehydrogenase 2; COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase;KEGG: 00250; KEGG: 00330; UniPathway: UPA00261; Belongs to the aldehyde dehydrogenase family.
  
 
  0.904
glsA
TIGRFAM:TIGR03814:Glutaminase; COG:COG2066: Glutaminase [Amino acid transport and metabolism]; Pfam:PF04960:Glutaminase; Hamap:MF_00313:Glutaminase; SUPERFAMILY:SSF56601:Beta-lactamase/transpeptidase- like;KEGG: 00250; KEGG: 00330; KEGG: 00471; KEGG: 00910; Reactome: REACT_13; Reactome: REACT_13685; Gln_ase; Belongs to the glutaminase family.
     
 0.902
AHY46968.1
COG:COG0436: Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Pfam:PF00155:Aminotransferase, class I/classII; Pfam:PF00155:Aminotransferase, class I/classII; ProSitePatterns:PS00105:Aminotransferases, class-I, pyridoxal-phosphate-binding site; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
     
 0.902
AHY46157.1
COG:COG0155: Sulfite reductase beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Pfam:PF01077:Nitrite/sulphite reductase 4Fe-4S domain; Pfam:PF01077:Nitrite/sulphite reductase 4Fe-4S domain; PRINTS:PR00397:Nitrite/sulphite reductase iron-sulphur/siroheam-binding site; ProSitePatterns:PS00365:Nitrite/sulphite reductase iron-sulphur/siroheam-binding site; SUPERFAMILY:SSF56014:No Description.
     
  0.900
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.900
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (18%) [HD]
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