STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45753.1TIGRFAM:TIGR00121:Biotin--acetyl-CoA-carboxylase ligase; COG:COG0340: Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;KEGG: 00780; birA_ligase. (270 aa)    
Predicted Functional Partners:
AHY45970.1
TIGRFAM:TIGR03725:tRNA threonylcarbamoyl adenosine modification protein YeaZ; COG:COG1214: Inactive homolog of metal-dependent proteases putative molecular chaperone [Posttranslational modification protein turnover chaperones]; Pfam:PF00814:Gcp-like domain; SUPERFAMILY:SSF53067:No Description; T6A_YeaZ.
  
    0.970
AHY47470.1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 0.920
AHY46201.1
accC: acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.848
AHY45737.1
COG:COG4770: Acetyl/propionyl-CoA carboxylase alpha subunit [Lipid metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SMART:SM00878:Biotin carboxylase, C-terminal; SUPERFAMILY:SSF56059:No Description.
  
 0.843
AHY45731.1
COG:COG4799: Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Pfam:PF01039:Carboxyl transferase; Pfam:PF01039:Carboxyl transferase; PRINTS:PR01070:Acetyl-CoA carboxylase carboxyl transferase, beta subunit; ProSiteProfiles:PS50980:Acetyl-coenzyme A carboxyltransferase, N-terminal; SUPERFAMILY:SSF52096:No Description.
 
 
 0.841
AHY47601.1
Hypothetical protein; COG:COG1268: Uncharacterized conserved protein [General function prediction only]; Pfam:PF02632:BioY protein; Pfam:PF02632:BioY protein; PIRSF:PIRSF016661:BioY protein.
 
   
 0.841
AHY45321.1
accC: acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.839
AHY46910.1
COG:COG4770: Acetyl/propionyl-CoA carboxylase alpha subunit [Lipid metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSitePatterns:PS00188:Biotin-binding site; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SMART:SM00878:Biotin carboxylase, C-terminal; SUPERFAMILY:SSF56059:No Description.
  
 0.834
murB
murB: UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.797
AHY45320.1
BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
 
 0.786
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
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