STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45897.1PucR C-terminal helix-turn-helix domain; COG:COG2508: Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF13556:PucR C-terminal helix-turn-helix domain; SUPERFAMILY:SSF55781:No Description. (666 aa)    
Predicted Functional Partners:
AHY45898.1
Tannase and feruloyl esterase; COG:COG2931: RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF07519:Tannase/feruloyl esterase; PRINTS:PR00313:NodO calcium binding signature; ProSitePatterns:PS00330:Hemolysin-type calcium-binding conserved site; SUPERFAMILY:SSF51120:Serralysin-like metalloprotease, C-terminal.
 
     0.588
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
   
 
 0.539
AHY45899.1
MFS transporter, metabolite:H+ symporter (MHS) family protein; TIGRFAM:TIGR00883:Citrate-proton symport; COG:COG2223: Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Pfam:PF07690:Major facilitator superfamily; ProSiteProfiles:PS50850:Major facilitator superfamily domain; SUPERFAMILY:SSF103473:Major facilitator superfamily domain, general substrate transporter.
 
     0.509
AHY45753.1
TIGRFAM:TIGR00121:Biotin--acetyl-CoA-carboxylase ligase; COG:COG0340: Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;KEGG: 00780; birA_ligase.
  
  
 0.500
AHY46230.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08447:PAS fold-3; ProSiteProfiles:PS50112:PAS domain; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.471
AHY45891.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50112:PAS domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
     
 0.460
AHY45658.1
thyX: thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
  
     0.451
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
 
 0.438
AHY47079.1
PucR C-terminal helix-turn-helix domain; COG:COG2508: Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF13556:PucR C-terminal helix-turn-helix domain; ProSiteProfiles:PS50887:GGDEF domain.
 
     0.437
AHY47910.1
PucR C-terminal helix-turn-helix domain; COG:COG2508: Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF13556:PucR C-terminal helix-turn-helix domain; SUPERFAMILY:SSF46689:Homeodomain-like.
 
     0.431
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
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