STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nnrEYjeF family C-terminal domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] (511 aa)    
Predicted Functional Partners:
AHY47698.1
NUDIX domain; COG:COG1051: ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
  
 0.914
AHY47721.1
NUDIX domain; COG:COG1051: ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
  
 0.914
AHY45969.1
TIGRFAM:TIGR00150:tRNA threonylcarbamoyl adenosine modification protein YjeE; COG:COG0802: Predicted ATPase or kinase [General function prediction only]; Pfam:PF02367:tRNA threonylcarbamoyl adenosine modification protein YjeE; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; T6A_YjeE.
  
 
 0.841
acpS
Phosphopantetheine--protein transferase domain; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.828
groL
GroEL: chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.717
AHY45964.1
Alr: alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
    0.684
AHY45297.1
TIGRFAM:TIGR00384:Succinate dehydrogenase/fumarate reductase iron-sulphur protein; COG:COG0479: Succinate dehydrogenase/fumarate reductase Fe-S protein subunit [Energy production and conversion]; Pfam:PF13085:Succinate dehydogenase/fumarate reductase N-terminal; ProSitePatterns:PS00197:2Fe-2S ferredoxin, iron-sulphur binding site; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF54292:2Fe-2S ferredoxin-type domain.
  
  
 0.673
AHY45963.1
CBS domain; COG:COG2524: Predicted transcriptional regulator contains C-terminal CBS domains [Transcription]; Pfam:PF00571:Cystathionine beta-synthase, core; ProSiteProfiles:PS51371:Cystathionine beta-synthase, core; SMART:SM00116:Cystathionine beta-synthase, core; SUPERFAMILY:SSF54631:No Description.
 
     0.659
nuoD
NADH:ubiquinone oxidoreductase 49 kD subunit 7; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
  
 
 0.648
AHY45960.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF143597:No Description.
       0.642
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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