STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45969.1TIGRFAM:TIGR00150:tRNA threonylcarbamoyl adenosine modification protein YjeE; COG:COG0802: Predicted ATPase or kinase [General function prediction only]; Pfam:PF02367:tRNA threonylcarbamoyl adenosine modification protein YjeE; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; T6A_YjeE. (163 aa)    
Predicted Functional Partners:
AHY45970.1
TIGRFAM:TIGR03725:tRNA threonylcarbamoyl adenosine modification protein YeaZ; COG:COG1214: Inactive homolog of metal-dependent proteases putative molecular chaperone [Posttranslational modification protein turnover chaperones]; Pfam:PF00814:Gcp-like domain; SUPERFAMILY:SSF53067:No Description; T6A_YeaZ.
 
 0.998
tsaD
tRNA threonylcarbamoyl adenosine modification protein YgjD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.988
AHY45971.1
rimI: ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18.
  
  
 0.875
nnrE
YjeF family C-terminal domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
 
 0.841
AHY45964.1
Alr: alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
  
 0.821
AHY45968.1
TIGRFAM:TIGR00758:Uracil-DNA glycosylase, family 4 domain; COG:COG1573: Uracil-DNA glycosylase [DNA replication recombination and repair]; Pfam:PF03167:Uracil-DNA glycosylase-like; SMART:SM00986:Uracil-DNA glycosylase-like; SUPERFAMILY:SSF52141:Uracil-DNA glycosylase-like; UDG_fam4.
       0.785
AHY45967.1
COG:COG1983: Putative stress-responsive transcriptional regulator [Transcription / Signal transduction mechanisms]; Pfam:PF04024:Phage shock protein, PspC, N-terminal; Pfam:PF04024:Phage shock protein, PspC, N-terminal.
       0.733
AHY46875.1
COG:COG0009: Putative translation factor (SUA5) [Translation ribosomal structure and biogenesis]; Pfam:PF01300:YrdC-like domain; Pfam:PF01300:YrdC-like domain; ProSiteProfiles:PS51163:YrdC-like domain; SUPERFAMILY:SSF55821:DHBP synthase RibB-like alpha/beta domain; Belongs to the SUA5 family.
    
 0.640
recG
recG: ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
  
     0.515
AHY45966.1
HD domain; COG:COG2844: UTP:GlnB (protein PII) uridylyltransferase [Posttranslational modification protein turnover chaperones]; Pfam:PF01966:HD domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description.
       0.506
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
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