STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46006.1COG:COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; PIRSF:PIRSF000524:Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase; ProSitePatterns:PS00595:Aminotransferase class-V pyridoxal-phosphate binding site; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase. (385 aa)    
Predicted Functional Partners:
AHY46007.1
TIGRFAM:TIGR01327:D-3-phosphoglycerate dehydrogenase; COG:COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; ProSitePatterns:PS00670:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; SUPERFAMILY:SSF51735:No Description;KEGG: 00260; KEGG: 00680; UniPathway: UPA00135.
  
  
 0.827
AHY46008.1
Pfam:PF14168:YjzC-like protein.
       0.689
AHY46009.1
GGDEF: diguanylate cyclase (GGDEF) domain; TIGRFAM:TIGR00254:GGDEF domain; COG:COG2206: HD-GYP domain [Signal transduction mechanisms]; Pfam:PF13487:HD domain; ProSiteProfiles:PS50887:GGDEF domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description.
  
    0.651
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
  
  
 0.644
alaS
alaS: alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.615
purD
purD: phosphoribosylamine--glycine ligase; TIGRFAM:TIGR00877:Phosphoribosylglycinamide synthetase; COG:COG0151: Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Pfam:PF01071:Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Hamap:MF_00138:Phosphoribosylglycinamide synthetase; ProSitePatterns:PS00184:Phosphoribosylglycinamide synthetase, conserved site; ProSiteProfiles:PS50975:ATP-grasp fold; SUPERFAMILY:SSF56059:No Description;KEGG: 00230; MetaCyc: PWY-6121; UniPathway: UPA00074; Belongs to the GARS family.
  
    0.597
AHY45911.1
FAD dependent oxidoreductase; COG:COG0404: Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; Pfam:PF01266:FAD dependent oxidoreductase; SUPERFAMILY:SSF103025:No Description; Belongs to the GcvT family.
  
 
 0.589
AHY46005.1
COG:COG3217: Uncharacterized Fe-S protein [General function prediction only]; Pfam:PF03473:Molybdenum cofactor sulfurase, C-terminal; Pfam:PF03473:Molybdenum cofactor sulfurase, C-terminal; ProSiteProfiles:PS51340:Molybdenum cofactor sulfurase, C-terminal; SUPERFAMILY:SSF141673:No Description.
  
    0.515
AHY46215.1
COG:COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Energy production and conversion]; Pfam:PF01070:FMN-dependent dehydrogenase; Pfam:PF01070:FMN-dependent dehydrogenase; PIRSF:PIRSF000138:Alpha-hydroxy acid dehydrogenase, FMN-dependent; ProSitePatterns:PS00557:FMN-dependent alpha-hydroxy acid dehydrogenase, active site; ProSiteProfiles:PS51349:Alpha-hydroxy acid dehydrogenase, FMN-dependent; SUPERFAMILY:SSF51395:No Description.
  
 0.500
AHY47920.1
TIGRFAM:TIGR03966:Heme/flavin dehydrogenase, Rv0694; COG:COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Energy production and conversion]; Pfam:PF01070:FMN-dependent dehydrogenase; PIRSF:PIRSF000138:Alpha-hydroxy acid dehydrogenase, FMN-dependent; ProSiteProfiles:PS51349:Alpha-hydroxy acid dehydrogenase, FMN-dependent; SUPERFAMILY:SSF51395:No Description; actino_HemFlav.
  
 0.500
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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