STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46018.1COG:COG1136: ABC-type antimicrobial peptide transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase. (253 aa)    
Predicted Functional Partners:
AHY46017.1
MacB-like periplasmic core domain; COG:COG4591: ABC-type transport system involved in lipoprotein release permease component [Cell envelope biogenesis outer membrane]; Pfam:PF12704:MacB-like periplasmic core domain.
 
 
 0.997
AHY47806.1
TIGRFAM:TIGR01726:Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; COG:COG0765: ABC-type amino acid transport system permease component [Amino acid transport and metabolism]; Pfam:PF00528:Binding-protein-dependent transport systems inner membrane component; ProSiteProfiles:PS50928:Binding-protein-dependent transport systems inner membrane component; SUPERFAMILY:SSF161098:No Description; HEQRo_perm_3TM.
 
 
  
 0.906
AHY47539.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
0.744
AHY47949.1
COG:COG1131: ABC-type multidrug transport system ATPase component [Defense mechanisms]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSiteProfiles:PS50893:ABC transporter-like; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
0.734
AHY47975.1
ATPase family associated with various cellular activities (AAA); COG:COG1222: ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification protein turnover chaperones]; Pfam:PF00004:ATPase, AAA-type, core; ProSitePatterns:PS00674:ATPase, AAA-type, conserved site; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
     0.729
AHY47196.1
COG:COG1122: ABC-type cobalt transport system ATPase component [Inorganic ion transport and metabolism]; Pfam:PF00005:ABC transporter-like; Pfam:PF00005:ABC transporter-like; ProSitePatterns:PS00211:ABC transporter, conserved site; ProSiteProfiles:PS50893:ABC transporter-like; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
   
0.718
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   
 0.623
AHY46066.1
TIGRFAM:TIGR00010:Uncharacterised deoxyribonuclease TatD-type; COG:COG0084: Mg-dependent DNase [DNA replication recombination and repair]; Pfam:PF01026:TatD family; PIRSF:PIRSF005902:TatD family; SUPERFAMILY:SSF51556:No Description.
 
   0.563
rsmA
ksgA: dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
 
 
 0.546
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.518
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (26%) [HD]
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