STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46059.1sigma70-ECF: RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (367 aa)    
Predicted Functional Partners:
dnaG
dnaG: DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
  
 0.887
rpoB
rpoB: DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.874
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.857
rpoA
rpoA: DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.848
rpoZ
rpoZ: DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.778
AHY45624.1
MerR HTH family regulatory protein; COG:COG0789: Predicted transcriptional regulators [Transcription]; Pfam:PF13411:MerR HTH family regulatory protein; ProSitePatterns:PS00552:Transcription regulator HTH, MerR; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00422:Transcription regulator HTH, MerR; SUPERFAMILY:SSF51182:RmlC-like cupin domain.
  
 
 0.674
secA
secA: preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
 
 
 0.577
AHY46061.1
COG:COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes [Lipid metabolism]; Pfam:PF13091:Phospholipase D-like domain; Pfam:PF13091:Phospholipase D-like domain; ProSiteProfiles:PS50035:Phospholipase D/Transphosphatidylase; SUPERFAMILY:SSF56024:No Description.
  
  
 0.571
nusA
NusA: transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
 0.561
AHY46060.1
Protein of unknown function (DUF697); COG:COG3597: Uncharacterized protein/domain associated with GTPases [Function unknown]; Pfam:PF05128:Protein of unknown function DUF697.
       0.538
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.