STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46106.1COG:COG2082: Precorrin isomerase [Coenzyme metabolism]; Pfam:PF02570:Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; Pfam:PF02570:Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SUPERFAMILY:SSF63965:Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core. (210 aa)    
Predicted Functional Partners:
cobB
cobB: cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
 0.999
AHY46103.1
CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; TIGRFAM:TIGR02467:Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; COG:COG2242: Precorrin-6B methylase 2 [Coenzyme metabolism]; Pfam:PF00590:Tetrapyrrole methylase; PIRSF:PIRSF036428:Cobalamin (vitamin B12) biosynthesis CobL, precorrin-6Y C5,15-methyltransferase; SUPERFAMILY:SSF53790:Tetrapyrrole methylase.
 
 
 0.999
AHY46104.1
precorrin-3B C17-methyltransferase; TIGRFAM:TIGR01466:Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; COG:COG1010: Precorrin-3B methylase [Coenzyme metabolism]; Pfam:PF00590:Tetrapyrrole methylase; SUPERFAMILY:SSF159672:No Description; cobJ_cbiH.
  
 0.999
cobQ
cobQ: cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.997
cbiD
cbiD: cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
 0.996
AHY46107.1
Hypothetical protein; COG:COG2138: Uncharacterized conserved protein [Function unknown]; Pfam:PF01903:Cobalamin (vitamin B12) biosynthesis CbiX; Pfam:PF01903:Cobalamin (vitamin B12) biosynthesis CbiX; SUPERFAMILY:SSF53800:No Description.
   
 0.994
AHY46101.1
Precorrin-4 C11-methyltransferase; TIGRFAM:TIGR01465:Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; COG:COG2875: Precorrin-4 methylase [Coenzyme metabolism]; Pfam:PF00590:Tetrapyrrole methylase; ProSitePatterns:PS00839:Uroporphiryn-III C-methyltransferase, conserved site; SUPERFAMILY:SSF53790:Tetrapyrrole methylase; cobM_cbiF.
 
  
 0.991
AHY46100.1
Precorrin-2 C20-methyltransferase; TIGRFAM:TIGR01467:Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; COG:COG2243: Precorrin-2 methylase [Coenzyme metabolism]; Pfam:PF00590:Tetrapyrrole methylase; PIRSF:PIRSF036427:Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase; SUPERFAMILY:SSF53790:Tetrapyrrole methylase; cobI_cbiL.
 
  
 0.989
cobD
cobD: cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.970
AHY46095.1
TIGRFAM:TIGR02257:Cobaltochelatase, CobN subunit; COG:COG1429: Cobalamin biosynthesis protein CobN and related Mg-chelatases [Coenzyme metabolism]; Pfam:PF02514:CobN/magnesium chelatase;KEGG: 00860; UniPathway: UPA00148; cobalto_cobN.
 
  
 0.940
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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