STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46149.1Twitching motility protein; TIGRFAM:TIGR01420:Pilus retraction protein PilT; COG:COG2805: Tfp pilus assembly protein pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00437:Type II secretion system protein E; ProSitePatterns:PS00662:Type II secretion system protein E; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; pilT_fam. (361 aa)    
Predicted Functional Partners:
AHY46146.1
COG:COG1459: Type II secretory pathway component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00482:Type II secretion system F domain; Pfam:PF00482:Type II secretion system F domain; PRINTS:PR00812:GspF/PilC family; ProSitePatterns:PS00874:Type II secretion system conserved site.
  
 0.869
AHY46649.1
COG:COG1459: Type II secretory pathway component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00482:Type II secretion system F domain; Pfam:PF00482:Type II secretion system F domain; PRINTS:PR00812:GspF/PilC family; ProSitePatterns:PS00874:Type II secretion system conserved site.
  
 0.802
AHY46135.1
COG:COG1989: Type II secretory pathway prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification protein turnover chaperones / Intracellular trafficking and secretion]; Pfam:PF06750:Peptidase A24A, N-terminal; Pfam:PF06750:Peptidase A24A, N-terminal.
 
   
 0.801
AHY46755.1
TIGRFAM:TIGR01175:Type IV pilus assembly protein PilM; COG:COG4972: Tfp pilus assembly protein ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF11104:Type IV pilus assembly protein PilM; SUPERFAMILY:SSF53067:No Description.
 
   
 0.785
AHY46138.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG2165: Type II secretory pathway pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF13544:Prokaryotic N-terminal methylation site; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
 
  
 0.709
AHY46148.1
COG:COG2804: Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF00437:Type II secretion system protein E; Pfam:PF00437:Type II secretion system protein E; ProSitePatterns:PS00662:Type II secretion system protein E; SMART:SM00382:AAA+ ATPase domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
  
0.618
AHY47286.1
Prepilin-type N-terminal cleavage/methylation domain; TIGRFAM:TIGR02532:Prokaryotic N-terminal methylation site; COG:COG4969: Tfp pilus assembly protein major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF13544:Prokaryotic N-terminal methylation site; ProSitePatterns:PS00409:Prokaryotic N-terminal methylation site; SUPERFAMILY:SSF54523:No Description; IV_pilin_GFxxxE.
 
   
 0.565
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
     
 0.472
AHY45508.1
TIGRFAM:TIGR00229:PAS domain; COG:COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Pfam:PF13426:PAS domain; PRINTS:PR00038:Transcription regulator LuxR, C-terminal; ProSitePatterns:PS00622:Transcription regulator LuxR, C-terminal; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00421:Transcription regulator LuxR, C-terminal; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.405
AHY46809.1
TIGRFAM:TIGR00360:ComEC/Rec2-related protein; COG:COG0658: Predicted membrane metal-binding protein [General function prediction only]; Pfam:PF03772:ComEC/Rec2-related protein; ComEC_N-term.
     
 0.404
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
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