STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46150.1COG:COG0095: Lipoate-protein ligase A [Coenzyme metabolism]; SUPERFAMILY:SSF55681:No Description. (249 aa)    
Predicted Functional Partners:
lipA
lipA: lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.920
lipB
lipB: lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.919
AHY47964.1
Biotin/lipoate A/B protein ligase family; COG:COG0095: Lipoate-protein ligase A [Coenzyme metabolism]; Pfam:PF03099:Biotin/lipoate A/B protein ligase; SUPERFAMILY:SSF55681:No Description;UniPathway: UPA00538.
  
  
 
0.911
AHY47758.1
Dehydrogenase E1 component; COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF00676:Dehydrogenase, E1 component; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
  
 
 0.893
gcvH
gcvH: glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.807
AHY47640.1
COG:COG3428: Predicted membrane protein [Function unknown]; Pfam:PF03703:Bacterial PH domain; Pfam:PF03703:Bacterial PH domain; PIRSF:PIRSF026631:Uncharacterised conserved protein UCP026631.
  
     0.582
AHY47641.1
Hypothetical protein; COG:COG3402: Uncharacterized conserved protein [Function unknown]; Pfam:PF03703:Bacterial PH domain; Pfam:PF03703:Bacterial PH domain.
  
     0.513
AHY45713.1
COG:COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit [Energy production and conversion]; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; Pfam:PF02779:Transketolase-like, pyrimidine-binding domain; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 
 
 0.492
AHY45714.1
COG:COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes [Energy production and conversion]; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SUPERFAMILY:SSF52777:No Description.
 
 0.484
AHY46932.1
COG:COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes [Energy production and conversion]; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; Pfam:PF00198:2-oxoacid dehydrogenase acyltransferase, catalytic domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SUPERFAMILY:SSF52777:No Description.
 
 0.480
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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