STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46154.1TIGRFAM:TIGR01916:Coenzyme F420:L-glutamate ligase, bacterial and archeal; COG:COG1478: Uncharacterized conserved protein [Function unknown]; Pfam:PF01996:Coenzyme F420:L-glutamate ligase-like domain; SUPERFAMILY:SSF144010:No Description;KEGG: 00380; UniPathway: UPA00071. (248 aa)    
Predicted Functional Partners:
AHY46151.1
TIGRFAM:TIGR01819:LPPG:Fo 2-phospho-L-lactate transferase; COG:COG0391: Uncharacterized conserved protein [Function unknown]; Pfam:PF01933:LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052; Hamap:MF_01257:LPPG:Fo 2-phospho-L-lactate transferase; SUPERFAMILY:SSF142338:No Description;KEGG: 00440; KEGG: 00513; KEGG: 00564; KEGG: 00600; UniPathway: UPA00071.
 
 
 0.993
AHY46165.1
TIGRFAM:TIGR03668:F420-dependent enzyme, PPOX class, family Rv0121, probable; COG:COG0778: Nitroreductase [Energy production and conversion]; Pfam:PF00881:Nitroreductase-like; SUPERFAMILY:SSF55469:Nitroreductase-like.
  
  0.993
fbiD
2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.925
AHY46167.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; TIGRFAM:TIGR03551:CofH family; COG:COG1060: Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes [Coenzyme metabolism / General function prediction only]; Pfam:PF04055:Radical SAM; Hamap:MF_01612:CofH family; SMART:SM00729:Elongator protein 3/MiaB/NifB; SUPERFAMILY:SSF102114:No Description;KEGG: 00130; KEGG: 00270; KEGG: 00380; KEGG: 00740; KEGG: 00860; KEGG: 00900; KEGG: 00906; UniPathway: UPA00072.
 
   
 0.826
AHY45428.1
Putative F420-dependent oxidoreductase, Rv1855c family; TIGRFAM:TIGR03560:F420-dependent oxidoreductase-predicted, Rv1855c; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
 
   
 0.769
AHY46124.1
Putative F420-dependent oxidoreductase, MSMEG_2256 family; TIGRFAM:TIGR03617:Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
 
   
 0.755
aroE
aroE: shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.749
AHY47394.1
TIGRFAM:TIGR00026:Deazaflavin-dependent nitroreductase; Pfam:PF04075:Deazaflavin-dependent nitroreductase;KEGG: 00121; KEGG: 00231; KEGG: 00520; KEGG: 00592; KEGG: 00633; KEGG: 00860; KEGG: 00906; KEGG: 00950; KEGG: 00981; hi_GC_TIGR00026.
  
   
 0.739
AHY47978.1
Putative F420-dependent oxidoreductase, Rv1855c family; TIGRFAM:TIGR03560:F420-dependent oxidoreductase-predicted, Rv1855c; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
 
   
 0.735
AHY45354.1
F420-dependent oxidoreductase, CPS_4043 family; TIGRFAM:TIGR03842:F420-dependent oxidoreductase-predicted, CPS4043; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
 
   
 0.732
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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