STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46188.1Hypothetical Protein; Ab initio prediction:Prodigal:2.60. (149 aa)    
Predicted Functional Partners:
AHY46189.1
TIGRFAM:TIGR00928:Adenylosuccinate lyase; COG:COG0015: Adenylosuccinate lyase [Nucleotide transport and metabolism]; Pfam:PF00206:Fumarate lyase, N-terminal; PRINTS:PR00149:Fumarate lyase; ProSitePatterns:PS00163:Fumarate lyase, conserved site; SMART:SM00998:Adenylosuccinate lyase C-terminal; SUPERFAMILY:SSF48557:L-Aspartase-like;KEGG: 00230; KEGG: 00250; MetaCyc: PWY-6123; MetaCyc: PWY-841; UniPathway: UPA00074; UniPathway: UPA00075; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
       0.773
purC
TIGRFAM:TIGR00081:SAICAR synthetase; COG:COG0152: Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase [Nucleotide transport and metabolism]; Pfam:PF01259:SAICAR synthetase; Hamap:MF_00137:SAICAR synthetase; ProSitePatterns:PS01057:SAICAR synthetase, conserved site; SUPERFAMILY:SSF56104:No Description;KEGG: 00230; MetaCyc: PWY-6123; UniPathway: UPA00074.
       0.773
purS
TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...]
       0.773
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
       0.773
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
       0.773
AHY46194.1
Putative restriction endonuclease; COG:COG4636: Uncharacterized protein conserved in cyanobacteria [Function unknown]; Pfam:PF05685:Domain of unknown function DUF820; SUPERFAMILY:SSF52980:Restriction endonuclease type II-like.
       0.588
purF
purF: amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.562
AHY46196.1
Acetyltransferase (GNAT) family; COG:COG0456: Acetyltransferases [General function prediction only]; Pfam:PF00583:GNAT domain; ProSiteProfiles:PS51186:GNAT domain; SUPERFAMILY:SSF55729:Acyl-CoA N-acyltransferase.
       0.562
purM
TIGRFAM:TIGR00878:Phosphoribosylformylglycinamidine cyclo-ligase; COG:COG0150: Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]; Pfam:PF02769:AIR synthase-related protein, C-terminal domain; SUPERFAMILY:SSF56042:AIR synthase-related protein, C-terminal domain;KEGG: 00230; MetaCyc: PWY-6121; UniPathway: UPA00074.
       0.562
purN
PurN: phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
       0.562
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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