STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46215.1COG:COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Energy production and conversion]; Pfam:PF01070:FMN-dependent dehydrogenase; Pfam:PF01070:FMN-dependent dehydrogenase; PIRSF:PIRSF000138:Alpha-hydroxy acid dehydrogenase, FMN-dependent; ProSitePatterns:PS00557:FMN-dependent alpha-hydroxy acid dehydrogenase, active site; ProSiteProfiles:PS51349:Alpha-hydroxy acid dehydrogenase, FMN-dependent; SUPERFAMILY:SSF51395:No Description. (386 aa)    
Predicted Functional Partners:
AHY47920.1
TIGRFAM:TIGR03966:Heme/flavin dehydrogenase, Rv0694; COG:COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases [Energy production and conversion]; Pfam:PF01070:FMN-dependent dehydrogenase; PIRSF:PIRSF000138:Alpha-hydroxy acid dehydrogenase, FMN-dependent; ProSiteProfiles:PS51349:Alpha-hydroxy acid dehydrogenase, FMN-dependent; SUPERFAMILY:SSF51395:No Description; actino_HemFlav.
  
  
 
0.920
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.907
AHY47178.1
COG:COG3875: Uncharacterized conserved protein [Function unknown]; Pfam:PF09861:Domain of unknown function DUF2088.
    
 0.902
AHY45951.1
COG:COG1254: Acylphosphatases [Energy production and conversion]; Pfam:PF00708:Acylphosphatase-like; Hamap:MF_01450:Acylphosphatase [yccX].; Pfam:PF00708:Acylphosphatase-like; PRINTS:PR00112:Acylphosphatase; ProSitePatterns:PS00151:Acylphosphatase, conserved site; ProSiteProfiles:PS51160:Acylphosphatase-like; SUPERFAMILY:SSF54975:Acylphosphatase-like.
     
  0.900
AHY47353.1
FAD linked oxidase, C-terminal domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF02913:FAD-linked oxidase, C-terminal; ProSitePatterns:PS00198:4Fe-4S ferredoxin, iron-sulphur binding, conserved site; ProSiteProfiles:PS51379:4Fe-4S ferredoxin-type, iron-sulpur binding domain; SUPERFAMILY:SSF55103:FAD-linked oxidase-like, C-terminal.
  
 0.627
AHY47773.1
FAD binding domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF01565:FAD linked oxidase, N-terminal; ProSiteProfiles:PS51387:FAD-binding, type 2; SUPERFAMILY:SSF56176:FAD-binding, type 2;MetaCyc: PWY-6386; UniPathway: UPA00219.
  
 0.627
AHY47548.1
lctP: transporter, lactate permease (LctP) family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.560
AHY46213.1
Transposase DDE domain; COG:COG3293: Transposase and inactivated derivatives [DNA replication recombination and repair]; Pfam:PF13586:Transposase DDE domain.
       0.541
AHY46214.1
Putative transposase of IS4/5 family (DUF4096); COG:COG3293: Transposase and inactivated derivatives [DNA replication recombination and repair]; Pfam:PF13340:Putative transposase IS4/IS5 family.
       0.541
AHY46525.1
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.528
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (28%) [HD]
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