STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaAmoaA: molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (336 aa)    
Predicted Functional Partners:
AHY47042.1
TIGRFAM:TIGR00581:Molybdenum cofactor biosynthesis C; COG:COG0315: Molybdenum cofactor biosynthesis enzyme [Coenzyme metabolism]; Pfam:PF01967:Molybdopterin cofactor biosynthesis C (MoaC) domain; SUPERFAMILY:SSF55040:Molybdopterin cofactor biosynthesis C (MoaC) domain;UniPathway: UPA00344.
 
 0.999
AHY45535.1
Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.948
AHY45672.1
COG:COG0314: Molybdopterin converting factor large subunit [Coenzyme metabolism]; Pfam:PF02391:Molybdopterin biosynthesis MoaE; Pfam:PF02391:Molybdopterin biosynthesis MoaE; SUPERFAMILY:SSF54690:Molybdopterin biosynthesis MoaE.
 
  
 0.923
AHY46401.1
Molybdenum cofactor synthesis domain; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
  
 0.923
folE
COG:COG0302: GTP cyclohydrolase I [Coenzyme metabolism]; Pfam:PF01227:GTP cyclohydrolase I/Nitrile oxidoreductase; Hamap:MF_00223:GTP cyclohydrolase I; Pfam:PF01227:GTP cyclohydrolase I/Nitrile oxidoreductase; ProSitePatterns:PS00859:GTP cyclohydrolase I, conserved site; SUPERFAMILY:SSF55620:No Description.
    
  0.907
ribBA
ribA: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.904
AHY46615.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.805
AHY46083.1
TIGRFAM:TIGR01064:Pyruvate kinase; COG:COG0469: Pyruvate kinase [Carbohydrate transport and metabolism]; Pfam:PF00224:Pyruvate kinase, barrel; PRINTS:PR01050:Pyruvate kinase; ProSitePatterns:PS00110:Pyruvate kinase, active site; SUPERFAMILY:SSF51621:Pyruvate/Phosphoenolpyruvate kinase-like domain;KEGG: 00010; KEGG: 00230; KEGG: 00620; KEGG: 00710; MetaCyc: PWY-2221; Reactome: REACT_474; UniPathway: UPA00109; pyruv_kin.
     
  0.800
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.800
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
  
 0.741
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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