STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46263.1COG:COG0651: Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit [Energy production and conversion / Inorganic ion transport and metabolism]; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; PRINTS:PR01434:NADH-ubiquinone oxidoreductase chain 5 signature. (499 aa)    
Predicted Functional Partners:
AHY46265.1
COG:COG1006: Multisubunit Na+/H+ antiporter MnhC subunit [Inorganic ion transport and metabolism]; Pfam:PF00420:NADH-ubiquinone oxidoreductase chain 4L/K; Pfam:PF00420:NADH-ubiquinone oxidoreductase chain 4L/K.
 
 
 0.983
AHY46269.1
COG:COG1863: Multisubunit Na+/H+ antiporter MnhE subunit [Inorganic ion transport and metabolism]; Pfam:PF01899:Cation antiporter.
 
 
 0.980
AHY46267.1
Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM:TIGR01300:Na+/H+ antiporter subunit; COG:COG1320: Multisubunit Na+/H+ antiporter MnhG subunit [Inorganic ion transport and metabolism]; Pfam:PF03334:Na+/H+ antiporter subunit; CPA3_mnhG_phaG.
 
 
 0.979
AHY46268.1
COG:COG2212: Multisubunit Na+/H+ antiporter MnhF subunit [Inorganic ion transport and metabolism]; Pfam:PF04066:Multiple resistance and pH regulation protein F; Pfam:PF04066:Multiple resistance and pH regulation protein F.
 
 
 0.978
AHY46266.1
Protein of unknown function (DUF4040); COG:COG1563: Predicted subunit of the Multisubunit Na+/H+ antiporter [Inorganic ion transport and metabolism]; Pfam:PF13244:Domain of unknown function DUF4040.
 
    0.960
nuoN
Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
 
 
0.958
AHY46849.1
TIGRFAM:TIGR01972:NADH-quinone oxidoreductase, chain M/4; COG:COG1008: NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; PRINTS:PR01437:NADH:ubiquinone oxidoreductase; NDH_I_M.
 
 
0.956
AHY46262.1
COG:COG0651: Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit [Energy production and conversion / Inorganic ion transport and metabolism]; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; PRINTS:PR01434:NADH-ubiquinone oxidoreductase chain 5 signature.
 
 
0.952
AHY46264.1
COG:COG0651: Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit [Energy production and conversion / Inorganic ion transport and metabolism]; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; Pfam:PF00361:NADH:ubiquinone/plastoquinone oxidoreductase; PRINTS:PR01437:NADH:ubiquinone oxidoreductase.
 
 
0.951
nuoK
NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.
  
 
 0.944
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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