STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46285.1COG:COG1824: Permease similar to cation transporters [Inorganic ion transport and metabolism]; Pfam:PF01769:SLC41 divalent cation transporters, integral membrane domain; SUPERFAMILY:SSF161093:No Description. (438 aa)    
Predicted Functional Partners:
AHY46284.1
TrkA-C domain; COG:COG3273: Uncharacterized conserved protein [Function unknown]; Pfam:PF02080:Regulator of K+ conductance, C-terminal; ProSiteProfiles:PS51202:Regulator of K+ conductance, C-terminal; SUPERFAMILY:SSF116726:No Description.
 
     0.923
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.531
AHY46286.1
COG:COG1055: Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Pfam:PF02040:Arsenite/antimonite efflux pump membrane protein, ArsB; Pfam:PF02040:Arsenite/antimonite efflux pump membrane protein, ArsB; PRINTS:PR00758:Arsenite/antimonite efflux pump membrane protein, ArsB.
       0.529
AHY46282.1
Pfam:PF09594:Protein of unknown function DUF2029;UniPathway: UPA00949.
       0.467
AHY46283.1
COG:COG5650: Predicted integral membrane protein [Function unknown]; Pfam:PF09594:Protein of unknown function DUF2029;UniPathway: UPA00949.
       0.467
AHY46287.1
Universal stress protein family; Pfam:PF00582:UspA; SUPERFAMILY:SSF52402:No Description.
       0.457
lysS
TIGRFAM:TIGR00467:Lysine-tRNA ligase; COG:COG1384: Lysyl-tRNA synthetase (class I) [Translation ribosomal structure and biogenesis]; Pfam:PF01921:Lysine-tRNA ligase; Hamap:MF_00177:Lysine-tRNA ligase; ProSitePatterns:PS00178:Aminoacyl-tRNA synthetase, class I, conserved site; SUPERFAMILY:SSF52374:No Description;KEGG: 00970; lysS_arch; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.452
AHY48045.1
COG:COG1836: Predicted membrane protein [Function unknown]; Pfam:PF01940:Protein of unknown function DUF92, TMEM19; Pfam:PF01940:Protein of unknown function DUF92, TMEM19.
  
     0.452
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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