STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
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Experiments
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[Homology]
Score
AHY46323.1COG:COG0304: 3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00109:Beta-ketoacyl synthase, N-terminal; Pfam:PF00109:Beta-ketoacyl synthase, N-terminal; SMART:SM00825:Polyketide synthase, beta-ketoacyl synthase domain; SUPERFAMILY:SSF53901:Thiolase-like; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (413 aa)    
Predicted Functional Partners:
AHY46668.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; PIRSF:PIRSF000446:Malonyl CoA-acyl carrier protein transacylase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 0.997
fabH
fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 0.995
AHY45525.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 0.992
AHY46670.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 0.970
fabZ
fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.952
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
 
 
 0.947
AHY45882.1
COG:COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis transport and catabolism / General function prediction only]; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; PRINTS:PR00081:Glucose/ribitol dehydrogenase; ProSitePatterns:PS00061:Short-chain dehydrogenase/reductase, conserved site; SMART:SM00822:Polyketide synthase/Fatty acid synthase, KR; SUPERFAMILY:SSF51735:No Description.
 0.945
AHY45908.1
COG:COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis transport and catabolism / General function prediction only]; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; Pfam:PF00106:Short-chain dehydrogenase/reductase SDR; PRINTS:PR00081:Glucose/ribitol dehydrogenase; ProSitePatterns:PS00061:Short-chain dehydrogenase/reductase, conserved site; SMART:SM00822:Polyketide synthase/Fatty acid synthase, KR; SUPERFAMILY:SSF51735:No Description.
 
 0.937
AHY46437.1
COG:COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis transport and catabolism / General function prediction only]; Pfam:PF13561:Enoyl-(Acyl carrier protein) reductase; Pfam:PF13561:Enoyl-(Acyl carrier protein) reductase; PRINTS:PR00081:Glucose/ribitol dehydrogenase; SMART:SM00822:Polyketide synthase/Fatty acid synthase, KR; SUPERFAMILY:SSF51735:No Description.
 
 0.937
AHY46672.1
fabF: beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
  
 
0.903
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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