STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46345.1TIGRFAM:TIGR02423:Protocatechuate 3,4-dioxygenase, alpha subunit; COG:COG3485: Protocatechuate 34-dioxygenase beta subunit [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00775:Intradiol ring-cleavage dioxygenase, C-terminal; ProSitePatterns:PS00083:Intradiol ring-cleavage dioxygenase, C-terminal; SUPERFAMILY:SSF49482:Intradiol ring-cleavage dioxygenase, core;KEGG: 00362; KEGG: 00624; KEGG: 00627; UniPathway: UPA00157; protocat_alph. (189 aa)    
Predicted Functional Partners:
AHY46346.1
TIGRFAM:TIGR02426:3-carboxy-cis,cis-muconate cycloisomerase; COG:COG0015: Adenylosuccinate lyase [Nucleotide transport and metabolism]; Pfam:PF00206:Fumarate lyase, N-terminal; PRINTS:PR00149:Fumarate lyase; SMART:SM00998:Adenylosuccinate lyase C-terminal; SUPERFAMILY:SSF48557:L-Aspartase-like;KEGG: 00362; protocat_pcaB.
 
 
 0.997
AHY46344.1
TIGRFAM:TIGR02422:Protocatechuate 3,4-dioxygenase, beta subunit; COG:COG3485: Protocatechuate 34-dioxygenase beta subunit [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00775:Intradiol ring-cleavage dioxygenase, C-terminal; ProSitePatterns:PS00083:Intradiol ring-cleavage dioxygenase, C-terminal; SUPERFAMILY:SSF49482:Intradiol ring-cleavage dioxygenase, core;KEGG: 00362; KEGG: 00624; KEGG: 00627; UniPathway: UPA00157; protocat_beta.
 
 
0.996
AHY46349.1
FAD binding domain; COG:COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Pfam:PF01494:Monooxygenase, FAD-binding; PRINTS:PR00420:Aromatic-ring hydroxylase-like; SUPERFAMILY:SSF51905:No Description.
 
 
 0.987
AHY46347.1
TIGRFAM:TIGR02425:4-carboxymuconolactone decarboxylase; COG:COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Pfam:PF02627:Carboxymuconolactone decarboxylase; SUPERFAMILY:SSF69118:No Description;KEGG: 00362; UniPathway: UPA00157; decarb_PcaC.
 
  
 0.950
AHY46992.1
Dioxygenase; COG:COG3485: Protocatechuate 34-dioxygenase beta subunit [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00775:Intradiol ring-cleavage dioxygenase, C-terminal; ProSitePatterns:PS00083:Intradiol ring-cleavage dioxygenase, C-terminal; SUPERFAMILY:SSF49482:Intradiol ring-cleavage dioxygenase, core.
 
  
 0.868
AHY46238.1
TIGRFAM:TIGR02427:3-oxoadipate enol-lactonase 1/2; COG:COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Pfam:PF12697:Alpha/beta hydrolase family; PRINTS:PR00111:Alpha/beta hydrolase fold-1; SUPERFAMILY:SSF53474:No Description; protocat_pcaD.
  
   
 0.692
AHY46348.1
Major Facilitator Superfamily; COG:COG2271: Sugar phosphate permease [Carbohydrate transport and metabolism]; Pfam:PF07690:Major facilitator superfamily; ProSitePatterns:PS00217:Sugar transporter, conserved site; ProSiteProfiles:PS50850:Major facilitator superfamily domain; SUPERFAMILY:SSF103473:Major facilitator superfamily domain, general substrate transporter.
 
     0.691
AHY46350.1
COG:COG1788: Acyl CoA:acetate/3-ketoacid CoA transferase alpha subunit [Lipid metabolism]; Pfam:PF01144:Coenzyme A transferase family I; Pfam:PF01144:Coenzyme A transferase family I; SMART:SM00882:Coenzyme A transferase family I; SUPERFAMILY:SSF100950:No Description.
 
  
 0.604
AHY46343.1
COG:COG0583: Transcriptional regulator [Transcription]; Pfam:PF03466:LysR, substrate-binding; Pfam:PF03466:LysR, substrate-binding; PRINTS:PR00039:Transcription regulator HTH, LysR; ProSiteProfiles:PS50931:Transcription regulator HTH, LysR; SUPERFAMILY:SSF53850:No Description; Belongs to the LysR transcriptional regulatory family.
     
 0.544
aroE
aroE: shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.475
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.