STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46356.1COG:COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF08240:Alcohol dehydrogenase GroES-like; Pfam:PF08240:Alcohol dehydrogenase GroES-like; ProSitePatterns:PS00059:Alcohol dehydrogenase, zinc-type, conserved site; SMART:SM00829:Polyketide synthase, enoylreductase; SUPERFAMILY:SSF50129:GroES-like. (342 aa)    
Predicted Functional Partners:
AHY47749.1
COG:COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF08240:Alcohol dehydrogenase GroES-like; Pfam:PF08240:Alcohol dehydrogenase GroES-like; ProSitePatterns:PS00059:Alcohol dehydrogenase, zinc-type, conserved site; SMART:SM00829:Polyketide synthase, enoylreductase; SUPERFAMILY:SSF50129:GroES-like.
  
  
 
0.926
AHY45814.1
COG:COG0524: Sugar kinases ribokinase family [Carbohydrate transport and metabolism]; Pfam:PF00294:Carbohydrate kinase PfkB; Pfam:PF00294:Carbohydrate kinase PfkB; ProSitePatterns:PS00583:Carbohydrate/puine kinase, PfkB, conserved site; SUPERFAMILY:SSF53613:No Description.
 
 
 0.918
AHY46936.1
TIGRFAM:TIGR01427:Phosphotransferase system, fructose IIC component; COG:COG1299: Phosphotransferase system fructose-specific IIC component [Carbohydrate transport and metabolism]; Pfam:PF02302:Phosphotransferase system, EIIB component, type 2/3; ProSiteProfiles:PS51099:Phosphotransferase system, EIIB component, type 2; SUPERFAMILY:SSF52794:No Description; PTS_IIC_fructo.
   
 
  0.903
AHY46937.1
TIGRFAM:TIGR00848:Phosphotransferase system, IIA component fructose subfamily; COG:COG1762: Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Pfam:PF00359:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; ProSiteProfiles:PS51094:Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; SUPERFAMILY:SSF55804:Phosphotransferase/anion transporter;KEGG: 00030; KEGG: 00540; KEGG: 00760.
  
 
  0.903
AHY46353.1
COG:COG3181: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF03401:Bordetella uptake gene; Pfam:PF03401:Bordetella uptake gene; PIRSF:PIRSF017082:Bordetella uptake gene; SUPERFAMILY:SSF53850:No Description.
       0.773
AHY46354.1
Tripartite tricarboxylate transporter TctB family; Pfam:PF07331:Protein of unknown function DUF1468.
       0.773
AHY46355.1
COG:COG3333: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF01970:Protein of unknown function DUF112, transmembrane; Pfam:PF01970:Protein of unknown function DUF112, transmembrane.
       0.773
AHY46357.1
Xylose isomerase-like TIM barrel; COG:COG1082: Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; SUPERFAMILY:SSF51658:Xylose isomerase-like, TIM barrel domain.
       0.654
AHY47404.1
COG:COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; Pfam:PF00107:Alcohol dehydrogenase, C-terminal; SMART:SM00829:Polyketide synthase, enoylreductase; SUPERFAMILY:SSF51735:No Description.
  
     0.652
aroE
aroE: shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.452
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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