STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1, subtype I-C/DVULG; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (344 aa)    
Predicted Functional Partners:
cas2
Cas2: CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
AHY46364.1
Cas4: CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 0.998
AHY46363.1
CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG; TIGRFAM:TIGR02589:CRISPR-associated protein Csd2; COG:COG3649: Uncharacterized protein predicted to be involved in DNA repair [DNA replication recombination and repair]; Pfam:PF05107:CRISPR-associated protein TM1801; cas_Csd2.
 
   
 0.958
AHY46361.1
CRISPR-associated protein Cas5, subtype I-C/DVULG; TIGRFAM:TIGR01876:CRISPR-associated protein, Cas5d-type; Pfam:PF09704:CRISPR-associated protein, Cas5; PIRSF:PIRSF029950:CRISPR-associated protein, Cas5d-type; cas_Cas5d.
 
   
 0.955
AHY46362.1
CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG; TIGRFAM:TIGR01863:CRISPR-associated protein, Csd1-type; Pfam:PF09709:CRISPR-associated protein, Csd1-type; cas_Csd1.
 
     0.955
AHY46360.1
TIGRFAM:TIGR01587:Helicase Cas3, CRISPR-associated, core; COG:COG1203: Predicted helicases [General function prediction only]; Pfam:PF00270:DNA/RNA helicase, DEAD/DEAH box type, N-terminal; ProSiteProfiles:PS51194:Helicase, C-terminal; SMART:SM00487:Helicase, superfamily 1/2, ATP-binding domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; cas3_core.
 
  
 0.953
AHY45795.1
Bacterial nucleoid DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.450
AHY47128.1
Putative dehydrogenase-related protein; COG:COG0673: Predicted dehydrogenases and related proteins [General function prediction only]; Pfam:PF01408:Oxidoreductase, N-terminal; Pfam:PF01408:Oxidoreductase, N-terminal; SUPERFAMILY:SSF51735:No Description.
   
 
 0.402
AHY47683.1
Oxidoreductase family, NAD-binding Rossmann fold; COG:COG0673: Predicted dehydrogenases and related proteins [General function prediction only]; Pfam:PF01408:Oxidoreductase, N-terminal; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF51735:No Description.
   
 
 0.402
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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