STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46398.1Cyclin-dependent kinase inhibitor 3 (CDKN3); COG:COG2453: Predicted protein-tyrosine phosphatase [Signal transduction mechanisms]; Pfam:PF05706:CDKN3 domain; ProSiteProfiles:PS50056:Protein-tyrosine/Dual specificity phosphatase; SUPERFAMILY:SSF52799:No Description. (199 aa)    
Predicted Functional Partners:
AHY46397.1
COG:COG1397: ADP-ribosylglycohydrolase [Posttranslational modification protein turnover chaperones]; Pfam:PF03747:ADP-ribosylation/Crystallin J1; Pfam:PF03747:ADP-ribosylation/Crystallin J1; SUPERFAMILY:SSF101478:ADP-ribosylation/Crystallin J1.
 
     0.918
lepA
lepA: GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.661
AHY46399.1
COG:COG3238: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF04657:Protein of unknown function DUF606; Pfam:PF04657:Protein of unknown function DUF606.
       0.542
AHY46401.1
Molybdenum cofactor synthesis domain; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
       0.532
AHY46400.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.531
AHY46402.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
       0.531
AHY46470.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
  
     0.510
AHY47737.1
COG:COG1397: ADP-ribosylglycohydrolase [Posttranslational modification protein turnover chaperones]; Pfam:PF03747:ADP-ribosylation/Crystallin J1; Pfam:PF03747:ADP-ribosylation/Crystallin J1; SUPERFAMILY:SSF101478:ADP-ribosylation/Crystallin J1.
  
 
 0.487
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.482
AHY47087.1
COG:COG0749: DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication recombination and repair]; Pfam:PF00476:DNA-directed DNA polymerase, family A, palm domain; PRINTS:PR00868:DNA polymerase A; ProSitePatterns:PS00447:DNA-directed DNA polymerase, family A, conserved site; SMART:SM00475:5'-3' exonuclease, N-terminal; SUPERFAMILY:SSF56672:No Description.
    
 
 0.456
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.