STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46406.1Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (407 aa)    
Predicted Functional Partners:
AHY45315.1
Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
 
0.920
AHY46528.1
COG:COG0405: Gamma-glutamyltransferase [Amino acid transport and metabolism]; Pfam:PF01019:Gamma-glutamyltranspeptidase; Pfam:PF01019:Gamma-glutamyltranspeptidase; PRINTS:PR01210:Gamma-glutamyltranspeptidase; SUPERFAMILY:SSF56235:No Description.
 
  
 0.919
AHY47553.1
Gamma-glutamyltransferase; TIGRFAM:TIGR00066:Gamma-glutamyltranspeptidase; COG:COG0405: Gamma-glutamyltransferase [Amino acid transport and metabolism]; Pfam:PF01019:Gamma-glutamyltranspeptidase; PRINTS:PR01210:Gamma-glutamyltranspeptidase; ProSitePatterns:PS00462:Gamma-glutamyltranspeptidase; SUPERFAMILY:SSF56235:No Description;KEGG: 00430; KEGG: 00450; KEGG: 00460; KEGG: 00480; KEGG: 00590; MetaCyc: PWY-4041; MetaCyc: PWY-5826; g_glut_trans.
 
  
 0.919
AHY47766.1
Gamma-glutamyltransferase; TIGRFAM:TIGR00066:Gamma-glutamyltranspeptidase; COG:COG0405: Gamma-glutamyltransferase [Amino acid transport and metabolism]; Pfam:PF01019:Gamma-glutamyltranspeptidase; PRINTS:PR01210:Gamma-glutamyltranspeptidase; SUPERFAMILY:SSF56235:No Description;KEGG: 00430; KEGG: 00450; KEGG: 00460; KEGG: 00480; KEGG: 00590; MetaCyc: PWY-4041; MetaCyc: PWY-5826; g_glut_trans.
    
 0.908
AHY46204.1
Uncharacterized proteins homologs of lactam utilization protein B; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
AHY47750.1
TIGRFAM:TIGR01893:Peptidase M20C, Xaa-His dipeptidase; COG:COG2195: Di- and tripeptidases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; PIRSF:PIRSF016599:Peptidase M20C, Xaa-His dipeptidase; PRINTS:PR00934:Peptidase M20C, Xaa-His dipeptidase; SUPERFAMILY:SSF53187:No Description.
     
  0.900
glsA
TIGRFAM:TIGR03814:Glutaminase; COG:COG2066: Glutaminase [Amino acid transport and metabolism]; Pfam:PF04960:Glutaminase; Hamap:MF_00313:Glutaminase; SUPERFAMILY:SSF56601:Beta-lactamase/transpeptidase- like;KEGG: 00250; KEGG: 00330; KEGG: 00471; KEGG: 00910; Reactome: REACT_13; Reactome: REACT_13685; Gln_ase; Belongs to the glutaminase family.
   
 
  0.806
AHY45604.1
TIGRFAM:TIGR01237:Delta-1-pyrroline-5-carboxylate dehydrogenase 2; COG:COG1012: NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Pfam:PF00171:Aldehyde dehydrogenase domain; ProSitePatterns:PS00687:Aldehyde dehydrogenase, conserved site; SUPERFAMILY:SSF53720:Aldehyde/histidinol dehydrogenase;KEGG: 00250; KEGG: 00330; UniPathway: UPA00261; Belongs to the aldehyde dehydrogenase family.
   
 
  0.805
AHY45708.1
COG:COG2902: NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism]; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; Pfam:PF05088:Bacterial NAD-glutamate dehydrogenase; PIRSF:PIRSF036761:Bacterial NAD-glutamate dehydrogenase; SUPERFAMILY:SSF51735:No Description.
     
  0.800
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.800
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.