STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46428.1COG:COG0705: Uncharacterized membrane protein (homolog of Drosophila rhomboid) [General function prediction only]; Pfam:PF01694:Peptidase S54, rhomboid domain; Pfam:PF01694:Peptidase S54, rhomboid domain; SUPERFAMILY:SSF144091:No Description. (209 aa)    
Predicted Functional Partners:
AHY46429.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.603
AHY47833.1
TIGRFAM:TIGR02727:5-formyltetrahydrofolate cyclo-ligase; COG:COG0212: 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Pfam:PF01812:5-formyltetrahydrofolate cyclo-ligase; PIRSF:PIRSF006806:5-formyltetrahydrofolate cyclo-ligase; SUPERFAMILY:SSF100950:No Description; MTHFS_bact; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
    0.482
AHY45804.1
COG:COG0860: N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis outer membrane]; Pfam:PF01520:Cell wall hydrolase/autolysin, catalytic; SMART:SM00646:Cell wall hydrolase/autolysin, catalytic; SUPERFAMILY:SSF53187:No Description.
  
   0.478
AHY47615.1
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; COG:COG1705: Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Pfam:PF01832:Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase.
  
   0.469
AHY46274.1
mttA/Hcf106 family; COG:COG1826: Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Pfam:PF02416:Sec-independent protein translocase protein TatA/B/E.
   
 
 0.445
tatA
tatAE: twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.445
AHY47048.1
mttA/Hcf106 family; COG:COG1826: Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Pfam:PF02416:Sec-independent protein translocase protein TatA/B/E; PRINTS:PR01506:Twin-arginine translocation protein TatB-like.
   
 
 0.445
tatA-2
tatAE: twin arginine-targeting protein translocase, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
   
 
 0.445
AHY46430.1
Nfo: apurinic endonuclease (APN1); TIGRFAM:TIGR00587:Endodeoxyribonuclease IV; COG:COG0648: Endonuclease IV [DNA replication recombination and repair]; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; ProSitePatterns:PS00729:AP endonuclease, family 2, zinc binding site; ProSiteProfiles:PS51432:Endodeoxyribonuclease IV; SMART:SM00518:Endodeoxyribonuclease IV; SUPERFAMILY:SSF51658:Xylose isomerase-like, TIM barrel domain.
       0.428
AHY47049.1
TIGRFAM:TIGR00277:Uncharacterised domain HDIG; COG:COG3481: Predicted HD-superfamily hydrolase [General function prediction only]; Pfam:PF01966:HD domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description;KEGG: 00230; KEGG: 00240.
  
     0.415
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.