STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46430.1Nfo: apurinic endonuclease (APN1); TIGRFAM:TIGR00587:Endodeoxyribonuclease IV; COG:COG0648: Endonuclease IV [DNA replication recombination and repair]; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; ProSitePatterns:PS00729:AP endonuclease, family 2, zinc binding site; ProSiteProfiles:PS51432:Endodeoxyribonuclease IV; SMART:SM00518:Endodeoxyribonuclease IV; SUPERFAMILY:SSF51658:Xylose isomerase-like, TIM barrel domain. (320 aa)    
Predicted Functional Partners:
AHY46431.1
Helix-turn-helix domain; COG:COG3620: Predicted transcriptional regulator with C-terminal CBS domains [Transcription]; Pfam:PF13560:Helix-turn-helix domain; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00530:Helix-turn-helix; SUPERFAMILY:SSF47413:Lambda repressor-like, DNA-binding domain.
       0.757
nth
Nth: endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.697
AHY47087.1
COG:COG0749: DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication recombination and repair]; Pfam:PF00476:DNA-directed DNA polymerase, family A, palm domain; PRINTS:PR00868:DNA polymerase A; ProSitePatterns:PS00447:DNA-directed DNA polymerase, family A, conserved site; SMART:SM00475:5'-3' exonuclease, N-terminal; SUPERFAMILY:SSF56672:No Description.
   
 
 0.583
AHY45487.1
Periplasmic binding protein; COG:COG0614: ABC-type Fe3+-hydroxamate transport system periplasmic component [Inorganic ion transport and metabolism]; Pfam:PF01497:ABC transporter periplasmic binding domain; ProSiteProfiles:PS50983:ABC transporter periplasmic binding domain; SUPERFAMILY:SSF53807:No Description.
 
      0.557
AHY45796.1
TIGRFAM:TIGR02127:Orotidine 5'-phosphate decarboxylase, type 2; COG:COG0284: Orotidine-5'-phosphate decarboxylase [Nucleotide transport and metabolism]; Pfam:PF00215:Orotidine 5'-phosphate decarboxylase domain; SMART:SM00934:Orotidine 5'-phosphate decarboxylase domain; SUPERFAMILY:SSF51366:Ribulose-phosphate binding barrel;KEGG: 00240; MetaCyc: PWY-5686; UniPathway: UPA00070; pyrF_sub2.
     
 0.518
AHY46429.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.518
AHY46101.1
Precorrin-4 C11-methyltransferase; TIGRFAM:TIGR01465:Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; COG:COG2875: Precorrin-4 methylase [Coenzyme metabolism]; Pfam:PF00590:Tetrapyrrole methylase; ProSitePatterns:PS00839:Uroporphiryn-III C-methyltransferase, conserved site; SUPERFAMILY:SSF53790:Tetrapyrrole methylase; cobM_cbiF.
      
 0.510
AHY47460.1
TIGRFAM:TIGR03440:Ergothioneine biosynthesis protein EgtB; COG:COG1262: Uncharacterized conserved protein [Function unknown]; Pfam:PF03781:Formylglycine-generating sulphatase enzyme domain; SUPERFAMILY:SSF56436:C-type lectin fold; egtB_TIGR03440.
      
 0.510
AHY45816.1
Dinuclear metal center protein, YbgI/SA1388 family; TIGRFAM:TIGR00486:Ngg1p interacting factor 3, NIF3; COG:COG3323: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF01784:Ngg1p interacting factor 3, NIF3; PIRSF:PIRSF037489:Uncharacterised protein family UPF0135, NIF3; SUPERFAMILY:SSF102705:Ngg1p interacting factor 3, NIF3; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
     
 0.485
AHY45359.1
PHP domain; COG:COG1796: DNA polymerase IV (family X) [DNA replication recombination and repair]; Pfam:PF02811:PHP, C-terminal; PIRSF:PIRSF005047:Uncharacterised conserved protein UCP005047, YshC; SMART:SM00483:DNA-directed DNA polymerase X; SUPERFAMILY:SSF89550:Polymerase/histidinol phosphatase-like.
   
  
 0.466
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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