STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46431.1Helix-turn-helix domain; COG:COG3620: Predicted transcriptional regulator with C-terminal CBS domains [Transcription]; Pfam:PF13560:Helix-turn-helix domain; ProSiteProfiles:PS50943:Helix-turn-helix; SMART:SM00530:Helix-turn-helix; SUPERFAMILY:SSF47413:Lambda repressor-like, DNA-binding domain. (110 aa)    
Predicted Functional Partners:
AHY46430.1
Nfo: apurinic endonuclease (APN1); TIGRFAM:TIGR00587:Endodeoxyribonuclease IV; COG:COG0648: Endonuclease IV [DNA replication recombination and repair]; Pfam:PF01261:Xylose isomerase-like, TIM barrel domain; ProSitePatterns:PS00729:AP endonuclease, family 2, zinc binding site; ProSiteProfiles:PS51432:Endodeoxyribonuclease IV; SMART:SM00518:Endodeoxyribonuclease IV; SUPERFAMILY:SSF51658:Xylose isomerase-like, TIM barrel domain.
       0.757
AHY45433.1
AAA domain; COG:COG0572: Uridine kinase [Nucleotide transport and metabolism]; Pfam:PF13207:AAA domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
    0.530
AHY46429.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60.
       0.508
AHY45420.1
COG:COG1414: Transcriptional regulator [Transcription]; Pfam:PF01614:Transcription regulator IclR, C-terminal; Pfam:PF01614:Transcription regulator IclR, C-terminal; ProSiteProfiles:PS51077:Transcription regulator IclR, N-terminal; SMART:SM00346:Transcription regulator IclR, N-terminal; SUPERFAMILY:SSF55781:No Description.
  
  
 0.423
AHY46428.1
COG:COG0705: Uncharacterized membrane protein (homolog of Drosophila rhomboid) [General function prediction only]; Pfam:PF01694:Peptidase S54, rhomboid domain; Pfam:PF01694:Peptidase S54, rhomboid domain; SUPERFAMILY:SSF144091:No Description.
       0.409
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.