STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46462.1COG:COG0647: Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Pfam:PF13344:HAD-superfamily hydrolase, subfamily IIA; Pfam:PF13344:HAD-superfamily hydrolase, subfamily IIA; SUPERFAMILY:SSF56784:HAD-like domain. (251 aa)    
Predicted Functional Partners:
AHY46461.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF53335:No Description.
       0.741
leuD
leuD: 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
      0.664
leuC
leuC: 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
      0.623
AHY46463.1
Secondary thiamine-phosphate synthase enzyme; TIGRFAM:TIGR00149:Uncharacterised protein family UPF0047; COG:COG0432: Uncharacterized conserved protein [Function unknown]; Pfam:PF01894:Uncharacterised protein family UPF0047; PIRSF:PIRSF004681:Uncharacterised protein family UPF0047; SUPERFAMILY:SSF111038:Uncharacterised protein family UPF0047; TIGR00149_YbjQ.
       0.590
AHY46460.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF53335:No Description.
  
    0.525
nadK
Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.461
AHY46742.1
recN: DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.460
cmk
TIGRFAM:TIGR00017:Cytidylate kinase; COG:COG0283: Cytidylate kinase [Nucleotide transport and metabolism]; Pfam:PF02224:Cytidylate kinase domain; Hamap:MF_00238:Cytidylate kinase; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase;KEGG: 00240.
  
    0.406
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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