STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46463.1Secondary thiamine-phosphate synthase enzyme; TIGRFAM:TIGR00149:Uncharacterised protein family UPF0047; COG:COG0432: Uncharacterized conserved protein [Function unknown]; Pfam:PF01894:Uncharacterised protein family UPF0047; PIRSF:PIRSF004681:Uncharacterised protein family UPF0047; SUPERFAMILY:SSF111038:Uncharacterised protein family UPF0047; TIGR00149_YbjQ. (134 aa)    
Predicted Functional Partners:
AHY46462.1
COG:COG0647: Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Pfam:PF13344:HAD-superfamily hydrolase, subfamily IIA; Pfam:PF13344:HAD-superfamily hydrolase, subfamily IIA; SUPERFAMILY:SSF56784:HAD-like domain.
       0.590
AHY46461.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF53335:No Description.
       0.567
nnrE
YjeF family C-terminal domain; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
 
     0.435
AHY46460.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF53335:No Description.
       0.406
AHY46459.1
Pfam:PF13704:Glycosyl transferase family 2; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
     0.401
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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