STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46473.1Major Facilitator Superfamily; COG:COG2271: Sugar phosphate permease [Carbohydrate transport and metabolism]; Pfam:PF07690:Major facilitator superfamily; ProSitePatterns:PS00216:Sugar transporter, conserved site; ProSiteProfiles:PS50850:Major facilitator superfamily domain; SUPERFAMILY:SSF103473:Major facilitator superfamily domain, general substrate transporter. (406 aa)    
Predicted Functional Partners:
AHY46472.1
Peptidase family S49; COG:COG0616: Periplasmic serine proteases (ClpP class) [Posttranslational modification protein turnover chaperones / Intracellular trafficking and secretion]; Pfam:PF01343:Peptidase S49; PIRSF:PIRSF001217:Peptidase S49, protease IV; SUPERFAMILY:SSF52096:No Description.
       0.773
AHY46471.1
COG:COG0735: Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism]; Pfam:PF01475:Ferric-uptake regulator; Pfam:PF01475:Ferric-uptake regulator; SUPERFAMILY:SSF46785:No Description; Belongs to the Fur family.
       0.557
AHY46448.1
Bacterial extracellular solute-binding protein; COG:COG1840: ABC-type Fe3+ transport system periplasmic component [Inorganic ion transport and metabolism]; Pfam:PF13343:Bacterial extracellular solute-binding protein; PIRSF:PIRSF002825:Ferric binding protein; SUPERFAMILY:SSF53850:No Description.
  
  
 0.515
AHY46474.1
COG:COG2409: Predicted drug exporters of the RND superfamily [General function prediction only]; Pfam:PF03176:Membrane transport protein, MMPL type; Pfam:PF03176:Membrane transport protein, MMPL type; ProSiteProfiles:PS50156:Sterol-sensing domain; SUPERFAMILY:SSF82866:No Description.
     
 0.493
AHY46478.1
TIGRFAM:TIGR00229:PAS domain; COG:COG4585: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF08448:PAS fold-4; ProSiteProfiles:PS50113:PAS-associated, C-terminal; SMART:SM00065:GAF domain; SUPERFAMILY:SSF55785:PAS domain; sensory_box.
  
  
 0.443
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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