STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
mobAMolybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (233 aa)    
Predicted Functional Partners:
AHY45535.1
Molybdenum cofactor synthesis domain; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
 0.965
AHY46518.1
Hypothetical protein; COG:COG1434: Uncharacterized conserved protein [Function unknown]; Pfam:PF02698:Domain of unknown function DUF218; Pfam:PF02698:Domain of unknown function DUF218.
       0.778
AHY46519.1
EamA-like transporter family; COG:COG5006: Predicted permease DMT superfamily [General function prediction only]; Pfam:PF00892:Drug/metabolite transporter; SUPERFAMILY:SSF103481:No Description.
  
    0.776
fdhD
Formate dehydrogenase family accessory protein FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
   
 
 0.670
AHY47783.1
Hypothetical Protein; Ab initio prediction:Prodigal:2.60; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
  
 
 0.655
moaA
moaA: molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.646
AHY47864.1
Molybdopterin oxidoreductase; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF00384:Molybdopterin oxidoreductase; SUPERFAMILY:SSF53706:No Description; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.592
AHY47863.1
Molybdopterin oxidoreductase Fe4S4 domain; COG:COG3383: Uncharacterized anaerobic dehydrogenase [General function prediction only]; Pfam:PF04879:Molybdopterin oxidoreductase, 4Fe-4S domain; ProSitePatterns:PS00551:Molybdopterin oxidoreductase, molybdopterin cofactor binding site; SMART:SM00926:Molybdopterin oxidoreductase, 4Fe-4S domain; SUPERFAMILY:SSF53706:No Description.
 
   
 0.580
AHY45660.1
COG:COG0607: Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Pfam:PF00581:Rhodanese-like domain; Pfam:PF00581:Rhodanese-like domain; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF52821:Rhodanese-like domain.
  
  
 0.532
AHY47427.1
ThiF family; COG:COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Pfam:PF00899:UBA/THIF-type NAD/FAD binding fold; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF69572:Molybdenum cofactor biosynthesis, MoeB.
  
  
 0.532
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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