STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46544.1Metallo-beta-lactamase superfamily; COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description. (341 aa)    
Predicted Functional Partners:
AHY46617.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
  
  
  0.939
AHY46402.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
  
  
 
0.918
AHY47772.1
COG:COG1052: Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; Pfam:PF02826:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; ProSitePatterns:PS00670:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; SUPERFAMILY:SSF51735:No Description.
  
 0.909
AHY47773.1
FAD binding domain; COG:COG0277: FAD/FMN-containing dehydrogenases [Energy production and conversion]; Pfam:PF01565:FAD linked oxidase, N-terminal; ProSiteProfiles:PS51387:FAD-binding, type 2; SUPERFAMILY:SSF56176:FAD-binding, type 2;MetaCyc: PWY-6386; UniPathway: UPA00219.
    
 0.905
AHY46162.1
Glyoxalase-like domain; COG:COG0346: Lactoylglutathione lyase and related lyases [Amino acid transport and metabolism]; Pfam:PF12681:Glyoxalase-like domain; ProSitePatterns:PS00934:Glyoxalase I, conserved site; SUPERFAMILY:SSF54593:No Description.
     
  0.900
AHY47178.1
COG:COG3875: Uncharacterized conserved protein [Function unknown]; Pfam:PF09861:Domain of unknown function DUF2088.
     
  0.900
AHY47282.1
Glyoxalase-like domain; COG:COG0346: Lactoylglutathione lyase and related lyases [Amino acid transport and metabolism]; Pfam:PF12681:Glyoxalase-like domain; ProSitePatterns:PS00934:Glyoxalase I, conserved site; SUPERFAMILY:SSF54593:No Description.
     
  0.900
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
  
 0.506
AHY46227.1
COG:COG0491: Zn-dependent hydrolases including glyoxylases [General function prediction only]; Pfam:PF00753:Beta-lactamase-like; Pfam:PF00753:Beta-lactamase-like; SMART:SM00849:Beta-lactamase-like; SUPERFAMILY:SSF56281:No Description.
  
     0.457
cobB-2
COG:COG0846: NAD-dependent protein deacetylases SIR2 family [Transcription]; Pfam:PF02146:Sirtuin family; Hamap:MF_01121:Sirtuin, classIII; Pfam:PF02146:Sirtuin family; ProSiteProfiles:PS50305:Sirtuin family, catalytic core domain; SUPERFAMILY:SSF52467:No Description; Belongs to the sirtuin family. Class III subfamily.
  
   0.402
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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