STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46585.1Hypothetical protein; COG:COG0011: Uncharacterized conserved protein [Function unknown]; Pfam:PF01910:Protein of unknown function DUF77; Pfam:PF01910:Protein of unknown function DUF77; SUPERFAMILY:SSF89957:Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative. (94 aa)    
Predicted Functional Partners:
AHY46581.1
COG:COG1319: Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs [Energy production and conversion]; Pfam:PF00941:Molybdopterin dehydrogenase, FAD-binding; Pfam:PF00941:Molybdopterin dehydrogenase, FAD-binding; ProSiteProfiles:PS51387:FAD-binding, type 2; SMART:SM01092:CO dehydrogenase flavoprotein, C-terminal; SUPERFAMILY:SSF56176:FAD-binding, type 2.
       0.773
AHY46582.1
COG:COG2080: Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs [Energy production and conversion]; Pfam:PF01799:[2Fe-2S]-binding; Pfam:PF01799:[2Fe-2S]-binding; ProSitePatterns:PS00197:2Fe-2S ferredoxin, iron-sulphur binding site; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF47741:[2Fe-2S]-binding.
       0.773
AHY46583.1
COG:COG0402: Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Pfam:PF01979:Amidohydrolase 1; Pfam:PF01979:Amidohydrolase 1; SUPERFAMILY:SSF51556:No Description.
       0.773
AHY46584.1
TIGRFAM:TIGR03196:Xanthine dehydrogenase D subunit; COG:COG1529: Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs [Energy production and conversion]; Pfam:PF02738:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; SMART:SM01008:Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; SUPERFAMILY:SSF56003:Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding;KEGG: 00230; MetaCyc: PWY-6237; MetaCyc: PWY-6596; UniPathway: UPA00604; UniPathway: UPA00604.
       0.773
AHY46586.1
TIGRFAM:TIGR03173:Xanthine permease; COG:COG2233: Xanthine/uracil permeases [Nucleotide transport and metabolism]; Pfam:PF00860:Xanthine/uracil/vitamin C permease; ProSitePatterns:PS01116:Xanthine/uracil permease; SUPERFAMILY:SSF158694:No Description.
       0.490
AHY46587.1
UHCUDC: OHCU decarboxylase; TIGRFAM:TIGR03164:2-oxo-4-hydroxy-4-carboxy-5- ureidoimidazoline decarboxylase, type 1; COG:COG3195: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF09349:Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; SUPERFAMILY:SSF158694:No Description;UniPathway: UPA00394.
       0.490
AHY46588.1
Urate oxidase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
       0.435
AHY46589.1
TIGRFAM:TIGR02962:Hydroxyisourate hydrolase; COG:COG2351: Transthyretin-like protein [General function prediction only]; Pfam:PF00576:Transthyretin/hydroxyisourate hydrolase, superfamily; PRINTS:PR00189:Transthyretin/hydroxyisourate hydrolase; ProSitePatterns:PS00768:Transthyretin, thyroxine binding site; SUPERFAMILY:SSF49472:Transthyretin/hydroxyisourate hydrolase, superfamily;KEGG: 00230; MetaCyc: PWY-5691; hdxy_isourate; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
       0.435
AHY46580.1
COG:COG0590: Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation ribosomal structure and biogenesis]; Pfam:PF00383:CMP/dCMP deaminase, zinc-binding; Pfam:PF00383:CMP/dCMP deaminase, zinc-binding; ProSitePatterns:PS00903:APOBEC/CMP deaminase, zinc-binding; SUPERFAMILY:SSF53927:Cytidine deaminase-like.
       0.418
AHY46590.1
TIGRFAM:TIGR01879:Amidase, hydantoinase/carbamoylase; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; PIRSF:PIRSF001235:Amidase, hydantoinase/carbamoylase; SUPERFAMILY:SSF53187:No Description.
       0.407
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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