STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46694.1TIGR00054: RIP metalloprotease RseP; TIGRFAM:TIGR00054:Peptidase M50, putative membrane-associated zinc metallopeptidase; COG:COG0750: Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis outer membrane]; Pfam:PF02163:Peptidase M50; ProSiteProfiles:PS50106:PDZ domain; SMART:SM00228:PDZ domain; SUPERFAMILY:SSF50156:PDZ domain. (348 aa)    
Predicted Functional Partners:
dxr
Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
 
  
 0.946
AHY46691.1
uppS: di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
  
 0.891
AHY46692.1
COG:COG0575: CDP-diglyceride synthetase [Lipid metabolism]; Pfam:PF01148:Phosphatidate cytidylyltransferase; Pfam:PF01148:Phosphatidate cytidylyltransferase; ProSitePatterns:PS01315:Phosphatidate cytidylyltransferase; Belongs to the CDS family.
  
    0.826
frr
Frr: ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.705
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.701
AHY47837.1
COG:COG0069: Glutamate synthase domain 2 [Amino acid transport and metabolism]; Pfam:PF01645:Glutamate synthase, central-C; ProSiteProfiles:PS51278:Glutamine amidotransferase type 2 domain; SUPERFAMILY:SSF51395:No Description;UniPathway: UPA00045.
  
  
 0.695
AHY46058.1
TIGRFAM:TIGR00225:C-terminal-processing peptidase S41A; COG:COG0793: Periplasmic protease [Cell envelope biogenesis outer membrane]; Pfam:PF03572:Interphotoreceptor retinol-binding; ProSiteProfiles:PS50106:PDZ domain; SMART:SM00245:Interphotoreceptor retinol-binding; SUPERFAMILY:SSF52096:No Description.
 
  
 0.680
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
 
     0.666
AHY46709.1
COG:COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Pfam:PF01580:Cell division protein FtsK/SpoIIIE; Pfam:PF01580:Cell division protein FtsK/SpoIIIE; ProSiteProfiles:PS50901:Cell division protein FtsK/SpoIIIE; SMART:SM00843:DNA translocase FtsK gamma; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; Belongs to the FtsK/SpoIIIE/SftA family.
 
    0.577
tsf
Tsf: translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.553
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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