STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46710.1Helix-turn-helix domain; COG:COG1426: Uncharacterized protein conserved in bacteria [Function unknown]; Pfam:PF13413:Helix-turn-helix domain. (210 aa)    
Predicted Functional Partners:
AHY46821.1
TIGRFAM:TIGR00904:Cell shape determining protein MreB/Mrl; COG:COG1077: Actin-like ATPase involved in cell morphogenesis [Cell division and chromosome partitioning]; Pfam:PF06723:Cell shape determining protein MreB/Mrl; PRINTS:PR01652:Cell shape determining protein MreB/Mrl; SUPERFAMILY:SSF53067:No Description.
 
 
 0.924
AHY46709.1
COG:COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Pfam:PF01580:Cell division protein FtsK/SpoIIIE; Pfam:PF01580:Cell division protein FtsK/SpoIIIE; ProSiteProfiles:PS50901:Cell division protein FtsK/SpoIIIE; SMART:SM00843:DNA translocase FtsK gamma; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; Belongs to the FtsK/SpoIIIE/SftA family.
     
 0.700
AHY46465.1
pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM:TIGR00560:CDP-diacylglycerol--glycerol-3- phosphate 3-phosphatidyltransferase; COG:COG0558: Phosphatidylglycerophosphate synthase [Lipid metabolism]; Pfam:PF01066:CDP-alcohol phosphatidyltransferase; PIRSF:PIRSF000847:CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; ProSitePatterns:PS00379:CDP-alcohol phosphatidyltransferase;KEGG: 00564; MetaCyc: PWY-5668; UniPathway: UPA00084; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.693
secA
secA: preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
  
 
 0.663
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
 
 0.640
AHY45542.1
COG:COG0558: Phosphatidylglycerophosphate synthase [Lipid metabolism]; Pfam:PF01066:CDP-alcohol phosphatidyltransferase; Pfam:PF01066:CDP-alcohol phosphatidyltransferase; ProSitePatterns:PS00379:CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.635
rpmC
TIGRFAM:TIGR00012:Ribosomal protein L29; COG:COG0255: Ribosomal protein L29 [Translation ribosomal structure and biogenesis]; Pfam:PF00831:Ribosomal protein L29; Hamap:MF_00374:Ribosomal protein L29; ProSitePatterns:PS00579:Ribosomal protein L29, conserved site; SUPERFAMILY:SSF46561:Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
    
   0.634
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
    
   0.634
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.566
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.564
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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