STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (450 aa)    
Predicted Functional Partners:
AHY46717.1
COG:COG0324: tRNA delta(2)-isopentenylpyrophosphate transferase [Translation ribosomal structure and biogenesis]; Pfam:PF01715:tRNA isopentenyltransferase; Pfam:PF01715:tRNA isopentenyltransferase; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
 
  
 0.904
rpmF
TIGRFAM:TIGR01031:Ribosomal protein L32p; COG:COG0333: Ribosomal protein L32 [Translation ribosomal structure and biogenesis]; Pfam:PF01783:Ribosomal protein L32p; Hamap:MF_00340:Ribosomal protein L32p; SUPERFAMILY:SSF57829:Ribosomal protein, zinc-binding domain; rpmF_bact; Belongs to the bacterial ribosomal protein bL32 family.
   
 
 0.872
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
 
 0.871
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.864
rplI
L9: ribosomal protein L9; Binds to the 23S rRNA.
 
 
 
 0.863
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
 
 0.858
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.852
rplW
Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
  
 
   0.852
rpmB
TIGRFAM:TIGR00009:Ribosomal protein L28; COG:COG0227: Ribosomal protein L28 [Translation ribosomal structure and biogenesis]; Pfam:PF00830:Ribosomal protein L28; Hamap:MF_00373:Ribosomal protein L28; SUPERFAMILY:SSF143800:No Description; Belongs to the bacterial ribosomal protein bL28 family.
   
 
 0.850
rplV
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
 
 0.850
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.