STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derRibosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (449 aa)    
Predicted Functional Partners:
cmk
TIGRFAM:TIGR00017:Cytidylate kinase; COG:COG0283: Cytidylate kinase [Nucleotide transport and metabolism]; Pfam:PF02224:Cytidylate kinase domain; Hamap:MF_00238:Cytidylate kinase; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase;KEGG: 00240.
  
 0.997
AHY46731.1
TIGRFAM:TIGR00093:Pseudouridine synthase, RsuA/RluB/E/F; COG:COG1187: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation ribosomal structure and biogenesis]; Pfam:PF00849:Pseudouridine synthase, RsuA/RluB/C/D/E/F; ProSitePatterns:PS01149:Pseudouridine synthase, RsuA/RluB/E/F, conserved site; ProSiteProfiles:PS50889:RNA-binding S4 domain; SMART:SM00363:RNA-binding S4 domain; SUPERFAMILY:SSF55120:Pseudouridine synthase, catalytic domain; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.971
AHY46732.1
COG:COG1386: Predicted transcriptional regulator containing the HTH domain [Transcription]; Pfam:PF04079:Chromosome segregation/condensation protein ScpB, prokaryote; Pfam:PF04079:Chromosome segregation/condensation protein ScpB, prokaryote; PIRSF:PIRSF019345:Chromosome segregation/condensation protein ScpB, prokaryote; SUPERFAMILY:SSF46785:No Description.
  
  
 0.876
dnaG
dnaG: DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
  
  
 0.866
AHY46728.1
COG:COG0204: 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Pfam:PF01553:Phospholipid/glycerol acyltransferase; Pfam:PF01553:Phospholipid/glycerol acyltransferase; SMART:SM00563:Phospholipid/glycerol acyltransferase; SUPERFAMILY:SSF69593:No Description.
  
    0.821
AHY46733.1
Hypothetical protein; COG:COG1354: Uncharacterized conserved protein [Function unknown].
  
  
 0.771
ftsY
ftsY: signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.746
ffh
Ffh: signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.727
aroA
aroA: 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.711
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.703
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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