STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46745.1COG:COG0142: Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Pfam:PF00348:Polyprenyl synthetase; Pfam:PF00348:Polyprenyl synthetase; ProSitePatterns:PS00723:Polyprenyl synthetase; SUPERFAMILY:SSF48576:Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (297 aa)    
Predicted Functional Partners:
AHY46691.1
uppS: di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.958
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
 
 0.941
AHY46014.1
COG:COG1562: Phytoene/squalene synthetase [Lipid metabolism]; Pfam:PF00494:Squalene/phytoene synthase; Pfam:PF00494:Squalene/phytoene synthase; ProSitePatterns:PS01045:Squalene/phytoene synthase, conserved site; SUPERFAMILY:SSF48576:Terpenoid synthase.
  
 0.907
AHY46744.1
Tly: hemolysin TlyA family protein; TIGRFAM:TIGR00478:Haemolysin A; COG:COG1189: Predicted rRNA methylase [Translation ribosomal structure and biogenesis]; Pfam:PF01728:Ribosomal RNA methyltransferase FtsJ domain; PIRSF:PIRSF005578:Haemolysin A; ProSiteProfiles:PS50889:RNA-binding S4 domain; SMART:SM00363:RNA-binding S4 domain; SUPERFAMILY:SSF55174:No Description.
 
    0.825
efp
Efp: translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
  
 0.818
nadK
Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
 
   0.817
nusB
nusB: transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
    0.804
AHY46742.1
recN: DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.787
AHY46739.1
COG:COG0463: Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis outer membrane]; Pfam:PF00535:Glycosyl transferase, family 2; SUPERFAMILY:SSF53448:No Description.
  
 
 0.770
pyrG
PyrG: CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.766
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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