STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46800.1TIGRFAM:TIGR00277:Uncharacterised domain HDIG; COG:COG1480: Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Pfam:PF07697:Metal-dependent phosphohydrolase, 7TM extracellular domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description;KEGG: 00230; KEGG: 00240. (759 aa)    
Predicted Functional Partners:
ybeY
TIGR00043: probable rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.841
AHY46798.1
COG:COG0818: Diacylglycerol kinase [Cell envelope biogenesis outer membrane]; Pfam:PF01219:Diacylglycerol kinase, prokaryotic; Pfam:PF01219:Diacylglycerol kinase, prokaryotic; ProSitePatterns:PS01069:Diacylglycerol kinase, prokaryotic.
  
    0.806
AHY46801.1
COG:COG1702: Phosphate starvation-inducible protein PhoH predicted ATPase [Signal transduction mechanisms]; Pfam:PF02562:PhoH-like protein; Pfam:PF02562:PhoH-like protein; SMART:SM00322:K Homology domain; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase.
     
 0.629
era
Era: GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.600
AHY46797.1
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.600
AHY46803.1
TIGR00046: RNA methyltransferase, RsmE family; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
 
     0.561
AHY46802.1
Hypothetical protein; COG:COG1610: Uncharacterized conserved protein [Function unknown]; Pfam:PF09424:Uncharacterised domain YOR215C, mitochondrial; Pfam:PF09424:Uncharacterised domain YOR215C, mitochondrial; SUPERFAMILY:SSF89095:Aspartyl/glutamyl-tRNA amidotransferase subunit B-related.
       0.551
dnaJ-2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
   0.494
AHY46793.1
Putative dGTPase; TIGRFAM:TIGR01353:Deoxyguanosinetriphosphate triphosphohydrolase; COG:COG0232: dGTP triphosphohydrolase [Nucleotide transport and metabolism]; Pfam:PF01966:HD domain; SMART:SM00471:HD/PDEase domain; SUPERFAMILY:SSF109604:No Description; dGTP_triPase; Belongs to the dGTPase family. Type 2 subfamily.
  
    0.465
recO
Reco: DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
       0.457
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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