STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46874.1Hypothetical Protein; Ab initio prediction:Prodigal:2.60. (146 aa)    
Predicted Functional Partners:
AHY46875.1
COG:COG0009: Putative translation factor (SUA5) [Translation ribosomal structure and biogenesis]; Pfam:PF01300:YrdC-like domain; Pfam:PF01300:YrdC-like domain; ProSiteProfiles:PS51163:YrdC-like domain; SUPERFAMILY:SSF55821:DHBP synthase RibB-like alpha/beta domain; Belongs to the SUA5 family.
       0.536
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.536
prfA
prfA: peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.488
AHY46871.1
COG:COG2131: Deoxycytidylate deaminase [Nucleotide transport and metabolism]; Pfam:PF00383:CMP/dCMP deaminase, zinc-binding; Pfam:PF00383:CMP/dCMP deaminase, zinc-binding; PIRSF:PIRSF006019:dCMP deaminase; ProSitePatterns:PS00903:APOBEC/CMP deaminase, zinc-binding; SUPERFAMILY:SSF53927:Cytidine deaminase-like.
       0.475
AHY46872.1
Upp: uracil phosphoribosyltransferase; TIGRFAM:TIGR01091:Uracil phosphoribosyl transferase; COG:COG0035: Uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Pfam:PF00156:Phosphoribosyltransferase domain; SUPERFAMILY:SSF53271:No Description;KEGG: 00240; UniPathway: UPA00574; Belongs to the UPRTase family.
       0.475
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.475
AHY46878.1
COG:COG3872: Predicted metal-dependent enzyme [General function prediction only]; Pfam:PF07136:Protein of unknown function DUF1385; Pfam:PF07136:Protein of unknown function DUF1385.
       0.414
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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