STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY46920.1COG:COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00455:AMP-binding, conserved site; SUPERFAMILY:SSF56801:No Description. (560 aa)    
Predicted Functional Partners:
AHY45894.1
TIGRFAM:TIGR01746:Thioester reductase domain; COG:COG3320: Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes [Secondary metabolites biosynthesis transport and catabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; ProSitePatterns:PS00012:Phosphopantetheine attachment site; ProSiteProfiles:PS50075:Acyl carrier protein-like; SMART:SM00823:Polyketide synthase, phosphopantetheine-binding domain; SUPERFAMILY:SSF56801:No Description.
 
0.939
AHY47122.1
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COG:COG1250: 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Pfam:PF02737:3-hydroxyacyl-CoA dehydrogenase, NAD binding; SUPERFAMILY:SSF51735:No Description;MetaCyc: PWY-1361; MetaCyc: PWY-5109; MetaCyc: PWY-5136; MetaCyc: PWY-5138; MetaCyc: PWY-5789; MetaCyc: PWY-6435; MetaCyc: PWY-735; UniPathway: UPA00659.
  
 
 0.573
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.538
AHY46668.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; PIRSF:PIRSF000446:Malonyl CoA-acyl carrier protein transacylase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 
  
 0.536
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.524
AHY45706.1
COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description.
 
 
0.515
aroA
aroA: 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
      0.508
AHY46921.1
Beta-lactamase enzyme family; COG:COG2367: Beta-lactamase class A [Defense mechanisms]; Pfam:PF13354:Beta-lactamase enzyme family; PRINTS:PR00118:Beta-lactamase, class-A/D; SUPERFAMILY:SSF56601:Beta-lactamase/transpeptidase-like.
       0.503
AHY46956.1
TIGRFAM:TIGR02262:Benzoate-CoA ligase family; COG:COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Pfam:PF00501:AMP-dependent synthetase/ligase; SUPERFAMILY:SSF56801:No Description; benz_CoA_lig.
 
 
0.491
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.483
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (24%) [HD]
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